与鼠疫耶尔森菌重复DNA序列IS100的同源性与假结核耶尔森菌对杀鼠疫菌素的敏感性相关。
Homology with a repeated Yersinia pestis DNA sequence IS100 correlates with pesticin sensitivity in Yersinia pseudotuberculosis.
作者信息
McDonough K A, Hare J M
机构信息
David Axelrod Institute, Wadsworth Center, New York State Department of Health, Albany 12201-2002, USA.
出版信息
J Bacteriol. 1997 Mar;179(6):2081-5. doi: 10.1128/jb.179.6.2081-2085.1997.
Abstract
We have identified IS100 sequences in a specific subset of Yersinia pseudotuberculosis isolates that were also sensitive to the Y. pestis-produced bacteriocin, pesticin. In contrast, Y. pseudotuberculosis strains which did not contain IS100 sequences were not sensitive to pesticin. We propose that IS100 serves as a molecular marker that identifies a subset of Y. pseudotuberculosis isolates that have a particularly close evolutionary and/or ecological relationship with Y. pestis.
摘要
我们在假结核耶尔森菌分离株的一个特定亚群中鉴定出了IS100序列，这些分离株对鼠疫耶尔森菌产生的细菌素——鼠疫菌素也敏感。相比之下，不含IS100序列的假结核耶尔森菌菌株对鼠疫菌素不敏感。我们提出，IS100可作为一种分子标记，用于识别与鼠疫耶尔森菌具有特别密切进化和/或生态关系的假结核耶尔森菌分离株亚群。
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