携带碳水化合物聚合物包覆的纳米颗粒的简易制备方法。

Simple preparation of nanoparticles coated with carbohydrate-carrying polymers.

作者信息

Cho C S, Jeong Y I, Ishihara T, Takei R, Park J U, Park K H, Maruyama A, Akaike T

机构信息

Department of Polymer Engineering, Chonnam National University, Kwangju, Korea.

出版信息

Biomaterials. 1997 Feb;18(4):323-6. doi: 10.1016/s0142-9612(96)00138-x.

DOI:10.1016/s0142-9612(96)00138-x

PMID:9068894

Abstract

Nanoparticles bearing carbohydrate chains on the surface can be prepared by the simple diafiltration method. The nanoparticles prepared by the present method displayed high yield, no-aggregation formation, small size, narrow size distribution, and one-step procedure. Also, the high density carbohydrate chains on the particles can be recognized by liver cells.

摘要

通过简单的渗滤法可制备表面带有碳水化合物链的纳米颗粒。用本方法制备的纳米颗粒具有高产率、无聚集体形成、尺寸小、尺寸分布窄以及一步法的特点。此外，颗粒上高密度的碳水化合物链可被肝细胞识别。