西索米星和奈替米星增强萘夫西林和苯唑西林的抗葡萄球菌活性。
Enhancement of antistaphylococcal activity of nafcillin and oxacillin by sisomicin and netilmicin.
作者信息
Watanakunakorn C, Glotzbecker C
出版信息
Antimicrob Agents Chemother. 1977 Sep;12(3):346-8. doi: 10.1128/AAC.12.3.346.
Abstract
The in vitro activity of sisomicin, netilmicin, nafcillin, and oxacillin against 35 strains of Staphylococcus aureus isolated from blood cultures of patients with endocarditis or septicemia was studied. The effects of combinations of either of the two newer aminoglycosides and either of the two penicillinase-resistant penicillins on the killing of S. aureus were investigated. All S. aureus strains were susceptible to the four antibiotics. Enhancement of antistaphylococcal activity was demonstrated by the antibiotic combinations.
摘要
研究了西索米星、奈替米星、萘夫西林和苯唑西林对从心内膜炎或败血症患者血培养物中分离出的35株金黄色葡萄球菌的体外活性。研究了两种新型氨基糖苷类抗生素中的任何一种与两种耐青霉素酶青霉素中的任何一种联合使用对金黄色葡萄球菌杀灭作用的影响。所有金黄色葡萄球菌菌株对这四种抗生素均敏感。抗生素联合使用显示出抗葡萄球菌活性增强。
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