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西索米星和奈替米星增强萘夫西林和苯唑西林的抗葡萄球菌活性。

Enhancement of antistaphylococcal activity of nafcillin and oxacillin by sisomicin and netilmicin.

作者信息

Watanakunakorn C, Glotzbecker C

出版信息

Antimicrob Agents Chemother. 1977 Sep;12(3):346-8. doi: 10.1128/AAC.12.3.346.

DOI:10.1128/AAC.12.3.346
PMID:907328
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC429916/
Abstract

The in vitro activity of sisomicin, netilmicin, nafcillin, and oxacillin against 35 strains of Staphylococcus aureus isolated from blood cultures of patients with endocarditis or septicemia was studied. The effects of combinations of either of the two newer aminoglycosides and either of the two penicillinase-resistant penicillins on the killing of S. aureus were investigated. All S. aureus strains were susceptible to the four antibiotics. Enhancement of antistaphylococcal activity was demonstrated by the antibiotic combinations.

摘要

研究了西索米星、奈替米星、萘夫西林和苯唑西林对从心内膜炎或败血症患者血培养物中分离出的35株金黄色葡萄球菌的体外活性。研究了两种新型氨基糖苷类抗生素中的任何一种与两种耐青霉素酶青霉素中的任何一种联合使用对金黄色葡萄球菌杀灭作用的影响。所有金黄色葡萄球菌菌株对这四种抗生素均敏感。抗生素联合使用显示出抗葡萄球菌活性增强。

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Enhancement of antistaphylococcal activity of nafcillin and oxacillin by sisomicin and netilmicin.西索米星和奈替米星增强萘夫西林和苯唑西林的抗葡萄球菌活性。
Antimicrob Agents Chemother. 1977 Sep;12(3):346-8. doi: 10.1128/AAC.12.3.346.
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In vitro activity of sisomicin and netilmicin alone and in combination with nafcillin, oxacillin and methicillin against enterococci.西索米星和奈替米星单独及与萘夫西林、苯唑西林和甲氧西林联合应用对肠球菌的体外活性。
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Comparative in vitro activity of nafcillin, oxacillin, and methicillin in combination with gentamicin and tobramycin against enterococci.萘夫西林、苯唑西林和甲氧西林联合庆大霉素及妥布霉素对肠球菌的体外比较活性
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Antimicrob Agents Chemother. 1975 Jun;7(6):828-32. doi: 10.1128/AAC.7.6.828.
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Combinations of lysostaphin with beta-lactams are synergistic against oxacillin-resistant Staphylococcus epidermidis.溶葡萄球菌酶与β-内酰胺类药物联合使用对耐苯唑西林表皮葡萄球菌具有协同作用。
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Comparative bactericidal activity of penicillin-netilmicin and penicillin-gentamicin against enterococci.青霉素-奈替米星与青霉素-庆大霉素对肠球菌的杀菌活性比较
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Nafcillin-gentamicin synergism in experimental staphylococcal endocarditis.萘夫西林-庆大霉素在实验性葡萄球菌性心内膜炎中的协同作用。
J Lab Clin Med. 1976 Jul;88(1):118-24.

引用本文的文献

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Antagonism between nafcillin or oxacillin and rifampin against Staphylococcus aureus.萘夫西林或苯唑西林与利福平对金黄色葡萄球菌的拮抗作用。
Antimicrob Agents Chemother. 1982 Nov;22(5):920-2. doi: 10.1128/AAC.22.5.920.
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Sisomicin, netilmicin and dibekacin. A review of their antibacterial activity and therapeutic use.西索米星、奈替米星和地贝卡星。对其抗菌活性和治疗用途的综述。
Drugs. 1984 Jun;27(6):548-78. doi: 10.2165/00003495-198427060-00003.
3
Netilmicin. A review of its antibacterial activity, pharmacokinetic properties and therapeutic use.奈替米星。对其抗菌活性、药代动力学特性及治疗用途的综述。
Drugs. 1989 Nov;38(5):703-56. doi: 10.2165/00003495-198938050-00003.
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Methicillin potentiates the effect of gentamicin on methicillin-resistant Staphylococcus aureus.甲氧西林可增强庆大霉素对耐甲氧西林金黄色葡萄球菌的作用。
Antimicrob Agents Chemother. 1979 Jan;15(1):34-41. doi: 10.1128/AAC.15.1.34.
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Use of synergistic antibiotics in the treatment of infections.联合使用抗生素治疗感染。
Can Med Assoc J. 1978 Nov 4;119(9):1004.

本文引用的文献

1
Comparative activity of sisomicin, gentamicin, kanamycin, and tobramycin.西索米星、庆大霉素、卡那霉素和妥布霉素的活性比较
Antimicrob Agents Chemother. 1972 Dec;2(6):431-7. doi: 10.1128/AAC.2.6.431.
2
Enhancement of the effects of anti-staphylococcal antibiotics by aminoglycosides.氨基糖苷类药物增强抗葡萄球菌抗生素的效果。
Antimicrob Agents Chemother. 1974 Dec;6(6):802-6. doi: 10.1128/AAC.6.6.802.
3
Comparative in vitro activity of Sch 20656, netilmicin, gentamicin, and tobramycin.Sch 20656、奈替米星、庆大霉素和妥布霉素的体外活性比较
Antimicrob Agents Chemother. 1976 Aug;10(2):382-3. doi: 10.1128/AAC.10.2.382.