Michel P, Dartigues J F, Lindoulsi A, Henry P
U 330 INSERM, Université de Bordeaux II, France.
Headache. 1997 Feb;37(2):71-8. doi: 10.1046/j.1526-4610.1997.3702071.x.
To assess the burden of migraine, we compared the productivity and the perceived health of 991 migraine sufferers (IHS criteria), 1,004 other-headache sufferers, and 1,757 nonheadache sufferers randomly chosen among volunteers from employees of the French national gas and electricity company. The extent of absenteeism was collected independently from the study subjects during a 4-year period. Performance at work was self-assessed at the end of the followup. The study subject also completed the Short-Form 36 Health Survey Questionnaire (SF36) and the Spielberger anxiety scale. The number of workdays lost due to migraine was not statistically different between the migraine and control groups, after adjustment for age, sex, and number of health impairments other than headaches. Performance was found to be greatly reduced in migraineurs. The quality of life was poorer and the anxiety level was higher in the migraine group than in the nonheadache group. There was no difference between migraineurs and other-headache sufferers for any variable. The lack of difference in absenteeism between migraineurs and nonheadache subjects calls into question prior research based on self-report. Moreover, it also calls into question the economic impact on migraine due to its direct costs found in previous studies without a control group. We found that the burden of migraine may be considered mainly in terms of reduced quality of life.
为评估偏头痛的负担，我们比较了991名偏头痛患者（采用国际头痛协会标准）、1004名其他类型头痛患者以及1757名非头痛患者的工作效率和自我感知健康状况，这些患者是从法国国家天然气和电力公司员工志愿者中随机选取的。在4年期间独立于研究对象收集旷工情况。随访结束时让研究对象自我评估工作表现。研究对象还完成了36项简短健康调查问卷（SF36）和斯皮尔伯格焦虑量表。在对年龄、性别以及除头痛外的健康损害数量进行调整后，偏头痛组和对照组因偏头痛导致的工作日损失数量在统计学上无差异。结果发现偏头痛患者的工作表现大幅下降。偏头痛组的生活质量比非头痛组差，焦虑水平也更高。偏头痛患者和其他类型头痛患者在任何变量上均无差异。偏头痛患者和非头痛患者在旷工方面缺乏差异，这对基于自我报告的先前研究提出了质疑。此外，这也对先前无对照组研究中发现的偏头痛直接成本所带来的经济影响提出了质疑。我们发现偏头痛的负担可能主要体现在生活质量下降方面。
