Tsukamoto T
Osaka Prefectural Institute of Public Health.
Kansenshogaku Zasshi. 1997 Feb;71(2):125-9. doi: 10.11150/kansenshogakuzasshi1970.71.125.
A portion of the neuS gene concerning Escherichia coli K1, was amplified by the PCR to detect the K1 antigen among extraintestinal infection with E. coli. The correlation between K1 antigen and O:H serotype was investigated. The predominant serotypes were O7:H-, O16:H6, O18ac:H7 from cerebrospinal fluid with meningitis, O16:H6 from blood with septicemia, O1 : H7, O7:H-, O16:H6, O18ac:H7, O75 : H- from urine with cystitis. The same O:H serotypes tended to be found frequently irrespective of source. K1 antigen was found O1:H7, O7:H-, O16:H6, O18ac:H7, and almost all the strains possessed to H6 or H7.
通过聚合酶链反应(PCR)扩增了大肠杆菌K1的neuS基因的一部分,以检测大肠杆菌肠外感染中的K1抗原。研究了K1抗原与O:H血清型之间的相关性。主要血清型为:脑膜炎脑脊液中的O7:H-、O16:H6、O18ac:H7;败血症血液中的O16:H6;膀胱炎尿液中的O1:H7、O7:H-、O16:H6、O18ac:H7、O75:H-。无论来源如何,相同的O:H血清型往往频繁出现。在O1:H7、O7:H-、O16:H6、O18ac:H7中发现了K1抗原,并且几乎所有菌株都具有H6或H7。