• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

Effects of disulfiram and related compounds on the metabolism in vivo of the colon carcinogen, 1,2-dimethylhydrazine.

作者信息

Fiala E S, Bobotas G, Kulakis C, Wattenberg L W, Weisburger J H

出版信息

Biochem Pharmacol. 1977 Oct 1;26(19):1763-8. doi: 10.1016/0006-2952(77)90343-4.

DOI:10.1016/0006-2952(77)90343-4
PMID:907715
Abstract
摘要

相似文献

1
Effects of disulfiram and related compounds on the metabolism in vivo of the colon carcinogen, 1,2-dimethylhydrazine.双硫仑及相关化合物对结肠致癌物1,2 - 二甲基肼体内代谢的影响。
Biochem Pharmacol. 1977 Oct 1;26(19):1763-8. doi: 10.1016/0006-2952(77)90343-4.
2
Investigations into the metabolism and mode of action of the colon carcinogens 1,2-dimethylhydrazine and azoxymethane.对结肠致癌物1,2 - 二甲基肼和氧化偶氮甲烷的代谢及作用方式的研究。
Cancer. 1977 Nov;40(5 Suppl):2436-45. doi: 10.1002/1097-0142(197711)40:5+<2436::aid-cncr2820400908>3.0.co;2-u.
3
[Action mechanism of the carcinogen 1,2-dimethylhydrazine].[致癌物质1,2 - 二甲基肼的作用机制]
Verh Dtsch Ges Pathol. 1978;62:494.
4
Detection and estimation of azomethane in expired air of 1,2-dimethylhydrazine-treated rats.检测和估算1,2 - 二甲基肼处理大鼠呼出气体中的偶氮甲烷。
J Natl Cancer Inst. 1976 Jun;56(6):1271-3. doi: 10.1093/jnci/56.6.1271.
5
Inhibition of the alkylation of nucleic acids and of the metabolism of 1,2-dimethylhydrazine by aminoacetonitrile.氨基乙腈对核酸烷基化作用及1,2 - 二甲基肼代谢的抑制作用
Chem Biol Interact. 1978 Nov;23(2):273-9. doi: 10.1016/0009-2797(78)90014-5.
6
Metabolism of 1,2-dimethylhydrazine by cultured human colon.1,2 - 二甲基肼在培养的人结肠中的代谢
Carcinogenesis. 1980 May;1(5):375-80. doi: 10.1093/carcin/1.5.375.
7
Inhibitors for the mutagenicities of colon carcinogens, 1,2-dimethylhydrazine and azoxymethane, in the host-mediated assay.在宿主介导试验中对结肠致癌物1,2 - 二甲基肼和氧化偶氮甲烷致突变性的抑制剂
Cancer Lett. 1979 Oct;7(6):325-30. doi: 10.1016/s0304-3835(79)80061-0.
8
Activation of the colon carcinogen 1,2-dimethylhydrazine in a rat colon cell-mediated mutagenesis assay.在大鼠结肠细胞介导的诱变试验中结肠致癌物1,2 - 二甲基肼的活化作用。
Cancer Res. 1986 Oct;46(10):5068-71.
9
Induction of colon tumors in 1,2-dimethylhydrazine-resistant Lobund Wistar rats by methylazoxymethanol acetate.
J Natl Cancer Inst. 1978 Aug;61(2):493-4.
10
Effect of retinoids on the induction of colon cancer in F344 rats by N-methyl-N-nitrosourea or by 1,2-dimethylhydrazine.
Carcinogenesis. 1981;2(11):1167-72. doi: 10.1093/carcin/2.11.1167.

引用本文的文献

1
Unexpected Liver and Kidney Pathology in C57BL/6J Mice Fed a High-fat Diet and Given Azoxymethane to Induce Colon Cancer.高脂肪饮食喂养并给予氧化偶氮甲烷诱导结肠癌的 C57BL/6J 小鼠出现意外的肝和肾病理变化。
Comp Med. 2022 Oct 1;72(5):330-335. doi: 10.30802/AALAS-CM-22-000040. Epub 2022 Sep 19.
2
On enzyme-based anticancer molecular dietary manipulations.基于酶的抗癌分子饮食调控
J Biomed Biotechnol. 2012;2012:790987. doi: 10.1155/2012/790987. Epub 2012 Sep 20.
3
Colorectal carcinogenesis: Review of human and experimental animal studies.
结直肠癌发生：人类和实验动物研究综述
J Carcinog. 2009;8:5. doi: 10.4103/1477-3163.49014.
4
Chemoprevention of azoxymethane-induced rat colon carcinogenesis by a xanthine oxidase inhibitor, 1'-acetoxychavicol acetate.黄嘌呤氧化酶抑制剂乙酸1'-乙酰氧基胡椒酚酯对氧化偶氮甲烷诱导的大鼠结肠癌发生的化学预防作用
Jpn J Cancer Res. 1997 Sep;88(9):821-30. doi: 10.1111/j.1349-7006.1997.tb00457.x.
5
Perspectives in cancer chemoprevention.癌症化学预防的前景
Environ Health Perspect. 1997 Jun;105 Suppl 4(Suppl 4):945-54. doi: 10.1289/ehp.97105s4945.
6
[Effect of disulfiram on the toxicity and carcinogenicity of N-methyl-n-nitrosobenzylamine in rats (author's transl)].双硫仑对大鼠N-甲基-N-亚硝基苄胺毒性和致癌性的影响（作者译）
J Cancer Res Clin Oncol. 1981;102(1):43-7. doi: 10.1007/BF00410533.
7
Further studies on dimethylnitrosamine metabolism, activation and its ability to cause liver injury.关于二甲基亚硝胺代谢、活化及其致肝损伤能力的进一步研究。
Arch Toxicol. 1981 Jun;47(3):159-68. doi: 10.1007/BF00368676.
8
Metabolism of methylazoxymethanol acetate in the F344 rat and strain-2 guinea pig and its inhibition by pyrazole and disulfiram.乙酸甲基偶氮甲醇在F344大鼠和2系豚鼠体内的代谢及其受吡唑和双硫仑的抑制作用。
J Cancer Res Clin Oncol. 1984;108(1):129-34. doi: 10.1007/BF00390984.
9
Differential effects of 4-iodopyrazole and 3-methylpyrazole on the metabolic activation of methylazoxymethanol to a DNA methylating species by rat liver and rat colon mucosa in vivo.4-碘吡唑和3-甲基吡唑对大鼠肝脏和大鼠结肠黏膜在体内将甲基偶氮甲醇代谢活化为DNA甲基化物质的不同作用。
J Cancer Res Clin Oncol. 1987;113(2):145-50. doi: 10.1007/BF00391436.
10
Modulation of 7,12-dimethylbenz[a]anthracene-induced transmammary carcinogenesis by disulfiram and butylated hydroxyanisole in mice.双硫仑和丁基羟基茴香醚对7,12-二甲基苯并[a]蒽诱导的小鼠经乳腺致癌作用的调节
Jpn J Cancer Res. 1989 Dec;80(12):1171-5. doi: 10.1111/j.1349-7006.1989.tb01650.x.