Smith S C, Kennelly P J, Potts M
Department of Biochemistry and Anaerobic Microbiology, Virginia Polytechnic Institute and State University, Blacksburg 24061, USA.
J Bacteriol. 1997 Apr;179(7):2418-20. doi: 10.1128/jb.179.7.2418-2420.1997.
Sulfolobus sulfataricus ATCC 35091, Haloferax volcanii, and Methanosarcina thermophila TM-1, representing the Euryarchaeota and Crenarchaeota subdomains of the Archaea, contain proteins which are phosphorylated on tyrosine. These data raise fundamental questions as to the origin and evolution of tyrosine phosphorylation, a protein modification that is of pivotal importance in the regulation of the physiology of eukaryotic cells.
嗜热栖热菌ATCC 35091、嗜盐栖热菌和嗜热嗜甲烷菌TM-1分别代表古菌域的广古菌门和泉古菌门，它们都含有在酪氨酸上发生磷酸化的蛋白质。这些数据引发了关于酪氨酸磷酸化起源和进化的基本问题，酪氨酸磷酸化是一种在真核细胞生理调节中至关重要的蛋白质修饰。
