Villegas L F, Fernández I D, Maldonado H, Torres R, Zavaleta A, Vaisberg A J, Hammond G B
Departamento de Ciencias Fisiológicas, Universidad Peruana Cayetano Heredia, Lima, Perú.
J Ethnopharmacol. 1997 Feb;55(3):193-200. doi: 10.1016/s0378-8741(96)01500-0.
Folk medicine practitioners in Perú employ plant preparations as wound-healing agents on superficial and internal wounds (gastric ulcers). The results of a scientific evaluation of the wound-healing activity of nine plants found in the Amazon jungle near Iquitos and in the Andes mountains is presented. The species studied were: Peperomia galioides, Mentzelia cordifolia, Mutisia acuminata, Himatanthus sucuuba, Spondias mombin, Eleutherine bulbosa, Muehlenbeckia tamnifolia, Anredera diffusa and Jatropha curcas. These plants have also been examined for their toxicological properties, their effect on blood pressure, smooth muscle and capillary permeability. Significant wound-healing activity was detected in Peperomia galioides, Anredera diffusa and Jatropha curcas. Extracts from Peperomia galioides and Anredera diffusa had no effect on cell proliferation and did not exhibit mutagenic activity.
秘鲁的民间医学从业者将植物制剂用作浅表伤口和内伤（胃溃疡）的愈合剂。本文展示了对在伊基托斯附近的亚马逊丛林和安第斯山脉发现的九种植物的伤口愈合活性进行科学评估的结果。所研究的物种有：细辛叶豆瓣绿、心叶月见草、尖叶穆蒂斯菊、黄花夹竹桃、马槟榔、美洲秋水仙、小叶扁藤、平卧落葵薯和麻风树。还对这些植物的毒理学特性、对血压、平滑肌和毛细血管通透性的影响进行了检测。在细辛叶豆瓣绿、平卧落葵薯和麻风树中检测到显著的伤口愈合活性。细辛叶豆瓣绿和平卧落葵薯的提取物对细胞增殖没有影响，也没有表现出诱变活性。
