Wade P A, Wolffe A P
Laboratory of Molecular Embryology, NICHHD, Bethesda, Maryland, 20892-5431, USA.
Curr Biol. 1997 Feb 1;7(2):R82-4. doi: 10.1016/s0960-9822(06)00042-x.
Several transcriptional regulators have been found to act as enzymes that acetylate histones. The targeted post-translational modification of histones within regulatory nucleoprotein complexes provides an attractive mechanism for controlling transcription within a chromatin environment.
已发现几种转录调节因子可作为使组蛋白乙酰化的酶。调节性核蛋白复合物中组蛋白的靶向翻译后修饰为在染色质环境中控制转录提供了一种引人注目的机制。
