处于控制状态的组蛋白乙酰转移酶。

Histone acetyltransferases in control.

作者信息

Wade P A, Wolffe A P

机构信息

Laboratory of Molecular Embryology, NICHHD, Bethesda, Maryland, 20892-5431, USA.

出版信息

Curr Biol. 1997 Feb 1;7(2):R82-4. doi: 10.1016/s0960-9822(06)00042-x.

DOI:10.1016/s0960-9822(06)00042-x

PMID:9081669

Abstract

Several transcriptional regulators have been found to act as enzymes that acetylate histones. The targeted post-translational modification of histones within regulatory nucleoprotein complexes provides an attractive mechanism for controlling transcription within a chromatin environment.

摘要

已发现几种转录调节因子可作为使组蛋白乙酰化的酶。调节性核蛋白复合物中组蛋白的靶向翻译后修饰为在染色质环境中控制转录提供了一种引人注目的机制。