Hailemariam S, Engeler D S, Koller T L, Sulser T, Spycher M, Schneider J
Department Pathologie, Universität, Zürich.
Pathologe. 1996 Nov;17(6):455-8. doi: 10.1007/s002920050186.
At the autopsy of a 68 year old man with plasmacytoma of the lambda light chain type we found polygonal interstitial cells with unusual crystalline inclusions, which were not readily identifiable and slightly resembled Leydig cells in conventional microscopy. In electron microscopy these could be identified as plasmacytoma cells, representing a testicular involvement. Comparable cells could be shown in the bone marrow. In immunochemistry we found a polyclonal reaction for lambda light chains suggesting a similar phenomenon as the so-called Russell bodies. As far as we know the literature, this finding in a testicular metastasis has not been described.
在对一名68岁的λ轻链型浆细胞瘤男性患者进行尸检时，我们发现多角形间质细胞内有异常的晶体包涵体，在传统显微镜下这些包涵体不易识别，且与Leydig细胞有轻微相似之处。在电子显微镜下，这些细胞可被鉴定为浆细胞瘤细胞，提示睾丸受累。在骨髓中也可发现类似的细胞。在免疫化学检查中，我们发现λ轻链呈多克隆反应，提示与所谓的Russell小体有相似现象。据我们所知，文献中尚未描述过睾丸转移中的这一发现。
