Jones I H, Hay D A, Kirkby K C, Daniels B A, Mowry B J
Division of Clinical Sciences, University of Tasmania, Hobart, Australia.
Aust N Z J Psychiatry. 1997 Feb;31(1):57-61. doi: 10.3109/00048679709073799.
The purpose of the present study was to determine whether there was a significant seasonal variation in the birth dates of patients with schizophrenia born in Tasmania.
The season of birth in Tasmanian-born patients with schizophrenia (n = 1412), born between 1919-1970, was compared with general population data.
No significant variation in month or quarter of birth was detected for the subjects with schizophrenia. Neither was there any significant seasonal excess when data from different decades were analysed separately, nor for subsidiary analyses of gender or paranoid/non paranoid subtype.
These results are compared with those of six other published studies of Australasian-born subjects identified through registers in different States. While both positive and negative results are reported, no clear pattern emerges. The relevance of season of birth to the development of schizophrenia in Australia remains an open question.
本研究旨在确定塔斯马尼亚州出生的精神分裂症患者的出生日期是否存在显著的季节性变化。
将1919年至1970年间出生的塔斯马尼亚州精神分裂症患者(n = 1412)的出生季节与一般人群数据进行比较。
未检测到精神分裂症患者在出生月份或季度上有显著变化。对不同十年的数据分别进行分析时,以及对性别或偏执型/非偏执型亚型进行辅助分析时,均未发现任何显著的季节性过剩情况。
将这些结果与通过不同州的登记册确定的其他六项关于澳大利亚出生人群的已发表研究结果进行了比较。虽然既有阳性结果也有阴性结果报道,但未出现明确模式。出生季节与澳大利亚精神分裂症发病的相关性仍然是一个悬而未决的问题。