Uluşahin A, Uluğ B
Hacettepe Universitesi, Tip Fak., Ankara, Turkey.
J Affect Disord. 1997 Jan;42(1):1-8. doi: 10.1016/s0165-0327(96)00099-7.
Effects of clinical and personality traits on the course of depression were investigated after a mean period of 30 months. 66 out of 119 depressive patients (according to DSM-III-R and ICD-10 diagnostic criteria) were re-assessed by the same clinicians of the index episode. Schedule for Standardized Assessment of Depressive Disorders (SADD) was the main instrument for the initial phase; the follow-up schedule of SADD was used for the second phase. In both phases personality was evaluated by Eysenck Personality Questionnaire (EPQ). Severity of the disorder was assessed by Beck Depression Inventory. We found a chronicity rate of 9.1%, recurrence rate of 31.8%. Common features of chronic depressives were female sex, being over 30 years of age, gradual and late onset, presence of anxiety and multiple life events. EPQ results of the subjects who were free of depression were compared at the follow-up assessment. The remitted recurrent depression group showed significantly lower neuroticism scores than remitted single depression group. Neurotic depression subgroup was significantly associated with higher neuroticism scores.
在平均30个月的时间后,对临床和人格特质对抑郁症病程的影响进行了调查。119名抑郁症患者(根据DSM-III-R和ICD-10诊断标准)中的66名由首次发作时的同一名临床医生进行重新评估。抑郁障碍标准化评估量表(SADD)是初始阶段的主要工具;SADD的随访量表用于第二阶段。在两个阶段中,均通过艾森克人格问卷(EPQ)对人格进行评估。通过贝克抑郁量表评估疾病的严重程度。我们发现慢性病发生率为9.1%,复发率为31.8%。慢性抑郁症患者的共同特征为女性、年龄超过30岁、起病缓慢且较晚、存在焦虑以及经历多个生活事件。在随访评估中,对无抑郁症状的受试者的EPQ结果进行了比较。缓解的复发性抑郁症组的神经质得分显著低于缓解的单次抑郁症组。神经症性抑郁症亚组与较高的神经质得分显著相关。