Krstić A, Smoljanić Z, Ajdinović B, Maglajlić S, Stefoski M, Lukac M, Vukanić D
University Children's Hospital, Belgrade.
Srp Arh Celok Lek. 1996;124 Suppl 1:231-4.
A multicystic dysplastic kidney (MCDK) is one of the most frequent causes of abdominal mass in the neonate. Prenatal echography permits early and frequent diagnostics. It is a nonfamilial disease without associated cystic disease of the pancreas, liver or lungs. Indications for elective surgery are clear when there is a symptomatic disease. However, treatment of asymptomatic patients is controversial. A rising number of authors prefer nonsurgical approach, leaving MCDK intact with a close follow-up of patients for possible severe complications (malignancy, hypertension, infection, pain, rupture). We treated 15 patients with MCDK from 1984 to 1994. Diagnosis was passed antenatally in 7 (47%) patients, accidentally in 2, and based on the presence of abdominal mass in 6 patients. Two patients had renal failure due to the abnormal contralateral kidney. Nine patients were operated on and 6 were treated nonsurgically. The risk of complications associated with nonsurgical treatment, easiness of efficient surgery at the age of 3-6 months, avoiding stress in the child and family due to long-term follow-up, all suggest operative treatment. We suggest to parents both operative and nonoperative options, explaining the risk and danger of both. We believe that nephrectomy is the best solution in a child with MCDK who is growing, develops hypertension, with uncertain diagnosis or when adequate follow-up is impossible.
多囊性发育不良肾(MCDK)是新生儿腹部肿块最常见的病因之一。产前超声检查可实现早期及频繁诊断。它是一种非家族性疾病,不伴有胰腺、肝脏或肺部的囊性疾病。当出现症状性疾病时,择期手术的指征明确。然而,无症状患者的治疗存在争议。越来越多的作者倾向于非手术方法,保留MCDK并密切随访患者,以预防可能出现的严重并发症(恶性肿瘤、高血压、感染、疼痛、破裂)。1984年至1994年期间,我们共治疗了15例MCDK患者。7例(47%)患者在产前确诊,2例偶然发现,6例根据腹部肿块确诊。2例患者因对侧肾脏异常而出现肾衰竭。9例患者接受了手术治疗,6例接受了非手术治疗。非手术治疗相关并发症的风险、3至6个月龄时高效手术的简便性、避免因长期随访给患儿及其家庭带来压力,所有这些都表明应采取手术治疗。我们向家长介绍手术和非手术两种选择,并解释两者的风险和危害。我们认为,对于正在生长发育、患有高血压、诊断不明确或无法进行充分随访的MCDK患儿,肾切除术是最佳解决方案。