• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

β-胡萝卜素无效：ATBC研究的后续影响

Beta-carotene did not work: aftermath of the ATBC study.

作者信息

Rautalahti M, Albanes D, Virtamo J, Taylor P R, Huttunen J K, Heinonen O P

机构信息

National Public Health Institute, Helsinki, Finland.

出版信息

Cancer Lett. 1997 Mar 19;114(1-2):235-6. doi: 10.1016/s0304-3835(97)04672-7.

DOI:10.1016/s0304-3835(97)04672-7
PMID:9103301
Abstract

The results of the ATBC study, the first large intervention trial of antioxidants, were intriguing. While the possibility that beta-carotene may in some circumstances enhance carcinogenesis has now been confirmed in another large trial, the mechanisms of action remain obscure.

摘要

ATBC研究是抗氧化剂的首次大型干预试验，其结果耐人寻味。虽然β-胡萝卜素在某些情况下可能会促进致癌作用这一可能性现已在另一项大型试验中得到证实，但其作用机制仍不清楚。

相似文献

1
Beta-carotene did not work: aftermath of the ATBC study.β-胡萝卜素无效：ATBC研究的后续影响
Cancer Lett. 1997 Mar 19;114(1-2):235-6. doi: 10.1016/s0304-3835(97)04672-7.
2
Alpha-Tocopherol and beta-carotene supplements and lung cancer incidence in the alpha-tocopherol, beta-carotene cancer prevention study: effects of base-line characteristics and study compliance.α-生育酚、β-胡萝卜素补充剂与α-生育酚、β-胡萝卜素癌症预防研究中的肺癌发病率：基线特征和研究依从性的影响
J Natl Cancer Inst. 1996 Nov 6;88(21):1560-70. doi: 10.1093/jnci/88.21.1560.
3
Vitamin E and beta-carotene supplementation and hospital-treated pneumonia incidence in male smokers.男性吸烟者补充维生素E和β-胡萝卜素与医院治疗的肺炎发病率
Chest. 2004 Feb;125(2):557-65. doi: 10.1378/chest.125.2.557.
4
Correcting for non-compliance in randomized trials: an application to the ATBC Study.
Stat Med. 1999 Nov 15;18(21):2879-97. doi: 10.1002/(sici)1097-0258(19991115)18:21<2879::aid-sim190>3.0.co;2-k.
5
Six-year supplementation with alpha-tocopherol and beta-carotene and age-related maculopathy.
Acta Ophthalmol Scand. 1998 Apr;76(2):224-9. doi: 10.1034/j.1600-0420.1998.760220.x.
6
Vitamin E supplementation may transiently increase tuberculosis risk in males who smoke heavily and have high dietary vitamin C intake.补充维生素E可能会使大量吸烟且膳食维生素C摄入量高的男性患结核病的风险暂时增加。
Br J Nutr. 2008 Oct;100(4):896-902. doi: 10.1017/S0007114508923709. Epub 2008 Feb 18.
7
Why did antioxidants not protect against lung cancer in the Alpha-Tocopherol, Beta-Carotene Cancer Prevention Study?在α-生育酚、β-胡萝卜素癌症预防研究中，抗氧化剂为何未能预防肺癌？
IARC Sci Publ. 1996(136):63-5.
8
The effects of supplementation with alpha-tocopherol and beta-carotene on the incidence and mortality of carcinoma of the pancreas in a randomized, controlled trial.在一项随机对照试验中，补充α-生育酚和β-胡萝卜素对胰腺癌发病率和死亡率的影响。
Cancer. 1999 Jul 1;86(1):37-42.
9
The effect of alpha-tocopherol and beta-carotene supplementation on colorectal adenomas in middle-aged male smokers.补充α-生育酚和β-胡萝卜素对中年男性吸烟者结肠直肠腺瘤的影响。
Cancer Epidemiol Biomarkers Prev. 1999 Jun;8(6):489-93.
10
Incidence of cancer and mortality following alpha-tocopherol and beta-carotene supplementation: a postintervention follow-up.补充α-生育酚和β-胡萝卜素后的癌症发病率及死亡率：干预后随访
JAMA. 2003 Jul 23;290(4):476-85. doi: 10.1001/jama.290.4.476.

引用本文的文献

1
Modelling potential β-carotene intake and cyanide exposure from consumption of biofortified cassava.模拟食用生物强化木薯的潜在β-胡萝卜素摄入量和氰化物暴露量。
J Nutr Sci. 2013 Feb 28;2:e6. doi: 10.1017/jns.2012.30. eCollection 2013.
2
Dietary chemoprevention of PhIP induced carcinogenesis in male Fischer 344 rats with tomato and broccoli.用番茄和西兰花对雄性 Fischer 344 大鼠进行膳食化学预防 PhIP 诱导的致癌作用。
PLoS One. 2013 Nov 27;8(11):e79842. doi: 10.1371/journal.pone.0079842. eCollection 2013.
3
Vitamin deficiencies in humans: can plant science help?
人类的维生素缺乏症：植物科学能提供帮助吗？
Plant Cell. 2012 Feb;24(2):395-414. doi: 10.1105/tpc.111.093120. Epub 2012 Feb 28.
4
Progress against cancer (1971-2011): how far have we come?癌症防治进展（1971-2011）：我们走了多远？
J Intern Med. 2012 Apr;271(4):392-9. doi: 10.1111/j.1365-2796.2011.02462.x. Epub 2011 Oct 20.
5
Treatment- and disease-related complications of prostate cancer.前列腺癌的治疗相关及疾病相关并发症
Rev Urol. 2006;8 Suppl 2(Suppl 2):S56-67.