Löffler K U, Witschel H
Universitäts-Augenklinik, Freiburg, Germany.
Br J Ophthalmol. 1991 Sep;75(9):568-71. doi: 10.1136/bjo.75.9.568.
We report on a 76-year-old patient with a squamous cell carcinoma of the left orbit. The tumour had no connection with the conjunctiva but was located at the site of an encircling band which had been inserted 13 years before. A major part of the tumour presented as a well circumscribed solid mass within the extraocular tissues next to the inferior equator, but the exenteration specimen also showed tumour extension within the adjacent choroid. Histological examination showed a well differentiated keratinising squamous cell carcinoma with numerous mitotic figures and many epithelial pearls. A thorough examination in search of a primary carcinoma of the lacrimal gland or the sinus, with invasion into the orbit, or an epithelial neoplasm elsewhere suggestive of metastatic disease into the choroid did not reveal any specific pathological findings. Thus the most probable origin of the tumour seems to be epithelium which had been misplaced during retinal detachment surgery and had subsequently undergone malignant transformation.
我们报告了一名76岁患有左眼眶鳞状细胞癌的患者。肿瘤与结膜无关联，而是位于13年前植入的环绕带所在部位。肿瘤的主要部分表现为赤道下方眼外组织内一个边界清晰的实性肿块，但眼球摘除标本也显示肿瘤已侵犯相邻脉络膜。组织学检查显示为高分化角化性鳞状细胞癌，有大量有丝分裂象和许多上皮珠。对泪腺或鼻窦原发性癌伴眼眶侵犯，或其他部位提示脉络膜转移的上皮性肿瘤进行全面检查，未发现任何特异性病理结果。因此，肿瘤最可能的起源似乎是视网膜脱离手术中错位的上皮，随后发生了恶性转化。
