Navashin S M, Sazykin Iu O, Fomina I P
Antibiotiki. 1977 Sep;22(9):781-9.
The main types of side reactions due to antibiotic therapy are described. The antibiotic groups most often being the cause of side reactions are presented. Dependence of the toxic (organotropic) effect of antibiotics on the therapy scheme, age and pathological changes in the mechanism of their excretion is indicated. The biochemical mechanisms of the side and selective effects of antibiotics are discussed.
描述了抗生素治疗引起的主要副反应类型。列出了最常导致副反应的抗生素类别。指出了抗生素的毒性(器官亲和性)作用对治疗方案、年龄及其排泄机制中病理变化的依赖性。讨论了抗生素副反应和选择性作用的生化机制。