vanSonnenberg E, Wittich G R, Chon K S, D'Agostino H B, Casola G, Easter D, Morgan R G, Walser E M, Nealon W H, Goodacre B, Stabile B E
Department of Radiology, University of Texas Medical Branch, Galveston 77555-0709, USA.
AJR Am J Roentgenol. 1997 Apr;168(4):979-84. doi: 10.2214/ajr.168.4.9124154.
The purpose of our study was to review and report the patient selection, techniques, and results of percutaneous drainage of pancreatic abscesses by retrospective review.
Fifty-nine patients (46 men and 13 women) with a mean age of 44 years old had 80 pancreatic abscesses that were drained percutaneously under radiologic guidance (CT, n = 77; sonography, n = 2; and fluoroscopy, n = 1). Abscesses had a wide spectrum of causes, with alcoholic pancreatitis being most common, trauma second most common, and gallstones third. Ten patients had undergone surgery for pancreatic necrosis or abscess. Patients with pancreatic pseudocysts, necrosis, or acute fluid collections were excluded from this study.
Of the 59 patients, 51 (86%) were cured with percutaneous drainage and antibiotic therapy. Of the patients who were not cured with percutaneous drainage, seven required surgery and one underwent repeat percutaneous drainage. In the 59 patients, complications included non-life-threatening bleeding in three patients. Ten of 59 patients (17%) had fistulas that spontaneously formed into the gastrointestinal tract. The duration of catheterization ranged from 4 to 119 days, with a mean duration of 33 days. The rate of mortality at 30 days after completion of percutaneous drainage was 8% (5 of 59).
Percutaneous drainage was an effective therapy for this defined group of patients with pancreatic abscesses. Factors leading to the relatively high success rate described in this study likely included selection of patients; catheters of adequate size, number, and location; careful follow-up with appropriate catheter manipulations; and an integrated, cooperative approach whereby surgeons were willing to permit drainage to effect its benefits, rather than operating prematurely.
我们研究的目的是通过回顾性分析,对胰腺脓肿经皮引流的患者选择、技术及结果进行回顾并报告。
59例患者(46例男性,13例女性),平均年龄44岁,共80个胰腺脓肿在放射学引导下(CT引导77例,超声引导2例,透视引导1例)进行了经皮引流。脓肿病因广泛,酒精性胰腺炎最为常见,其次是外伤,胆结石位列第三。10例患者曾因胰腺坏死或脓肿接受过手术。胰腺假性囊肿、坏死或急性液体积聚的患者被排除在本研究之外。
59例患者中,51例(86%)经皮引流及抗生素治疗后治愈。经皮引流未治愈的患者中,7例需要手术,1例接受了重复经皮引流。59例患者中,并发症包括3例无生命危险的出血。59例患者中有10例(17%)出现瘘管,自行通向胃肠道。置管时间为4至119天,平均33天。经皮引流完成后30天内的死亡率为8%(59例中的5例)。
经皮引流对于这一特定组别的胰腺脓肿患者是一种有效的治疗方法。本研究中所述成功率相对较高的因素可能包括患者的选择;导管尺寸、数量和位置合适;通过适当的导管操作进行仔细随访;以及一种综合、协作的方法,即外科医生愿意让引流发挥其益处,而不是过早进行手术。