Kindermann W, Keul J, Huber G
Eur J Appl Physiol Occup Physiol. 1977 Oct 31;37(3):197-204. doi: 10.1007/BF00421775.
The influence of bicarbonate and Tris-buffer infusions on the performance capacity for maximal, brief exercise (400 m run) was studied using 10 normal males in their twenties. Run time, maximal lactate concentration and heart rate remained unchanged after the buffer infusions. As a result of the induced elevated buffering capacity, the average pH after exercise was about 0.1 unit higher. Corresponding values for base excess and standard bicarbonate were found. The arterial pCO2 was higher after infusion as a result of the active respiratory compensation. Since the reduction in the work-related metabolic acidosis by the buffering substances caused no improvement in performance, the importance of pH as the performance-limiting factor must be questioned because the investigation gave no evidence for alterations of intracellular pH.
使用10名20多岁的正常男性，研究了碳酸氢盐和Tris缓冲液输注对最大强度短时间运动（400米跑）运动能力的影响。缓冲液输注后，跑步时间、最大乳酸浓度和心率保持不变。由于诱导的缓冲能力提高，运动后的平均pH值高出约0.1个单位。发现了碱剩余和标准碳酸氢盐的相应值。由于主动呼吸代偿，输注后动脉血二氧化碳分压较高。由于缓冲物质减轻与工作相关的代谢性酸中毒并未改善运动表现，因此必须质疑pH作为限制运动表现因素的重要性，因为该研究没有提供细胞内pH改变的证据。
