Nosovitsky V A, Ilegbusi O J, Jiang J, Stone P H, Feldman C L
Department of Medicine, Brigham and Women's Hospital, Boston, Massachusetts 02115, USA.
Comput Biomed Res. 1997 Feb;30(1):61-82. doi: 10.1006/cbmr.1997.1434.
To gain insight into the details of intracoronary flow we have used computational fluid dynamic techniques to determine the velocity and wall shear stress distributions in both steady- and phasic-flow models of a curved coronary artery with several degrees of stenosis. The steady-flow Reynolds number was 500 and the peak phasic flow Reynolds number was 700. Without stenosis and at 25% (area) stenosis wall shear stress and velocities are higher at the outer wall than the inner wall but retain the same direction as the superimposed flow. At higher stenoses laminar flow separation occurs and the inner wall is exposed to shear stresses that vary widely, both temporally and spatially.
为深入了解冠状动脉内血流的细节，我们运用计算流体动力学技术，来确定具有不同程度狭窄的弯曲冠状动脉在稳定流和脉动流模型中的速度及壁面切应力分布。稳定流雷诺数为500，脉动流峰值雷诺数为700。在无狭窄以及25%（面积）狭窄的情况下，外壁处的壁面切应力和速度高于内壁，但与叠加流方向保持一致。在更高程度的狭窄时，会发生层流分离，内壁会受到在时间和空间上变化很大的切应力作用。
