大鼠和家兔肌肉组织中鹅肌肽和肌肽的含量。

Anserine and carnosine contents in muscular tissue of rat and rabbit.

作者信息

Tamaki N, Nakamura M, Harada M, Kimura K, Kawano H

出版信息

J Nutr Sci Vitaminol (Tokyo). 1977;23(4):319-29. doi: 10.3177/jnsv.23.319.

DOI:10.3177/jnsv.23.319

Abstract

The effect of various muscle conditions on anserine and carnosine contents suggests that these peptides have some physiological role in muscular functions. These conditions are: 1) Although the anserine content in rat gastrocnemius muscle was not changed by ischiamic denervation, the carnosine content was significantly decreased. Carnosinase activity in the denerved gastrocnemius muscle was two times stronger than that of intact gastrocnemius muscle. 2) Carnosine content in rat gastrocnemius muscle was also decreased by forced swimming exercise. 3) Neither anserine nor carnosine was detected in sarcoma and granuloma. 4) In rabbit, anserine and carnosine contents in white muscle fibers were 12-17 and 1-2 mumole/g of wet tissue and were approximately 10 and 2 times more than those in red muscle fibers, respectively.

摘要

各种肌肉状况对鹅肌肽和肌肽含量的影响表明，这些肽在肌肉功能中具有一定的生理作用。这些状况如下：1）尽管大鼠腓肠肌中的鹅肌肽含量未因坐骨神经去神经支配而改变，但肌肽含量显著降低。去神经支配的腓肠肌中的肌肽酶活性比完整腓肠肌的强两倍。2）强迫游泳运动也会使大鼠腓肠肌中的肌肽含量降低。3）在肉瘤和肉芽肿中未检测到鹅肌肽和肌肽。4）在兔子中，白色肌纤维中的鹅肌肽和肌肽含量分别为每克湿组织12 - 17微摩尔和1 - 2微摩尔，分别比红色肌纤维中的含量高约10倍和2倍。