Kusuhara K, Takabayashi A, Ueda K, Hidaka Y, Minamishima I, Take H, Fujioka K, Imai S, Osato T
Department of Pediatrics, Faculty of Medicine, Kyushu University, Higashi-ku, Fukuoka, Japan.
Microbiol Immunol. 1997;41(4):309-12. doi: 10.1111/j.1348-0421.1997.tb01206.x.
In order to evaluate the possibility of Epstein-Barr virus (EBV) and human herpesvirus 6 (HHV-6) transmission via breast milk, a total of 331 serum specimens collected from bottle-fed and breast-fed children and their mothers, in 2 endemic areas of human T-cell lymphotropic virus type I (HTLV-I) in Japan, were assayed for antibodies to EBV and HHV-6. The seroprevalences of EBV and HHV-6 were over 95% both in the mothers of bottle-fed children and in those of breast-fed children. The seroprevalence of EBV at 12-23 months of age was 54.5% (36/66) and 55.8% (24/43) in breast-fed children and bottle-fed children, respectively. The seroprevalence of HHV-6 at 12-23 months of age was 90.9% (60/66) and 93.0% (40/43) in breast-fed children and bottle-fed children, respectively. No difference was observed between the seroprevalences of EBV and HHV-6 in breast-fed and bottle-fed children at 12-23 months of age. Our seroepidemiologic data indicate that breast milk is not a significant source of early EBV or HHV-6 infection in infancy.
为评估爱泼斯坦-巴尔病毒（EBV）和人类疱疹病毒6型（HHV-6）通过母乳传播的可能性，对日本两个I型人类嗜T淋巴细胞病毒（HTLV-I）流行地区的331份血清标本进行了检测，这些标本来自人工喂养和母乳喂养儿童及其母亲，检测其中EBV和HHV-6抗体。人工喂养儿童的母亲和母乳喂养儿童的母亲中，EBV和HHV-6的血清阳性率均超过95%。12至23个月大的母乳喂养儿童中EBV血清阳性率为54.5%（36/66），人工喂养儿童中为55.8%（24/43）。12至23个月大的母乳喂养儿童中HHV-6血清阳性率为90.9%（60/66），人工喂养儿童中为93.0%（40/43）。12至23个月大的母乳喂养儿童和人工喂养儿童中，EBV和HHV-6的血清阳性率未观察到差异。我们的血清流行病学数据表明，母乳不是婴儿期早期EBV或HHV-6感染的重要来源。
