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老化的皮肤。

The aging skin.

作者信息

Bergfeld W F

机构信息

Department of Dermatology, Cleveland Clinic Foundation, Ohio, USA.

出版信息

Int J Fertil Womens Med. 1997 Mar-Apr;42(2):57-66.

PMID:9160214
Abstract

In the past, sun exposure has been an integral part of the American life style. Along with increased leisure time, outdoor recreational sports, and sun bathing has come greater exposure to the sun. The cumulative effects of unprotected sun exposure coupled with the changes in the ozone layer have resulted in a large photodamaged population and an epidemic of the most dangerous skin cancer, malignant melanoma. Photodamage begins early, with a child's first unprotected sun exposure. Clinical studies show that 50% of an individual's ultraviolet light exposure occurs before the age of 18 years. This damage from acute and chronic ultraviolet light exposure has produced the explosion of skin cancers. Over the next 4 years, it is expected that skin cancer will become the most common type of cancer, and malignant melanoma will become the leading cause of death from skin cancer. This growing hazard to the public has profound medical and psychological ramifications. This paper will focus on prevention, identification, evaluation and treatment of photodamage to skin, as well as skin cancer. Special emphasis will be given to the National Skin Cancer Prevention Education Program.

摘要

过去,晒太阳一直是美国人生活方式中不可或缺的一部分。随着休闲时间的增加,户外休闲运动以及日光浴使得人们更多地暴露在阳光下。无防护的日光照射所产生的累积效应,再加上臭氧层的变化,导致了大量受光损伤的人群以及最危险的皮肤癌——恶性黑色素瘤的流行。光损伤很早就开始了,始于儿童第一次无防护的日光照射。临床研究表明,个体50%的紫外线暴露发生在18岁之前。急性和慢性紫外线暴露造成的这种损伤导致了皮肤癌的激增。预计在未来4年里,皮肤癌将成为最常见的癌症类型,而恶性黑色素瘤将成为皮肤癌致死的主要原因。这种对公众日益增加的危害具有深远的医学和心理影响。本文将重点关注皮肤光损伤以及皮肤癌的预防、识别、评估和治疗。特别强调国家皮肤癌预防教育计划。

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