Kokkarinen J I, Tukiainen H O, Terho E O
Department of Pulmonary Diseases, Kuopio University Hospital, Finland.
Scand J Work Environ Health. 1997 Apr;23(2):149-51. doi: 10.5271/sjweh.192.
This study assessed the incidence of asthma in patients with farmer's lung.
The study population consisted of 1031 patients who had occupational farmer's lung diagnosed from 1983 to 1988. The cases of farmer's lung were registered in the nationwide Register of Occupational Diseases by the Finnish Institute of Occupational Health, and all the patients in the study had received compensation from the insurance company for an occupational disease. The diagnosis of asthma was based on entitlement to a special refund for asthma medication costs from the national sickness insurance program.
Seventy-four cases of asthma were found among farmers with farmer's lung up to the end of the 5 years following the year of the diagnosis for farmer's lung. The prevalence of asthma was 1% in the year preceding the diagnosis. In the year of the diagnosis and during the 5 year of follow-up, asthma was diagnosed in an additional 6% of the patients.
The results of this study confirm previous findings of a low prevalence of asthma before the onset of farmer's lung in small groups of patients. However, the results also indicate that the incidence of asthma increases during the first years after an episode of farmers lung. For example, in the present study, asthma was apparent in 7% of the patients 5 years after the diagnosis of farmer's lung.
本研究评估农民肺患者中哮喘的发病率。
研究人群包括1983年至1988年被诊断患有职业性农民肺的1031名患者。农民肺病例由芬兰职业健康研究所登记在全国职业病登记册中,研究中的所有患者均已从保险公司获得职业病赔偿。哮喘的诊断基于有权从国家疾病保险计划获得哮喘药物费用的特殊退款。
在农民肺诊断年份后的5年结束时,在患有农民肺的农民中发现了74例哮喘病例。在诊断前一年,哮喘患病率为1%。在诊断当年及随后的5年随访期间,另外6%的患者被诊断出患有哮喘。
本研究结果证实了先前在一小部分患者中发现的农民肺发病前哮喘患病率较低的情况。然而,结果也表明,在农民肺发作后的头几年中,哮喘发病率会增加。例如,在本研究中,农民肺诊断5年后,7%的患者出现哮喘。