Tettelin H, Agostoni Carbone M L, Albermann K, Albers M, Arroyo J, Backes U, Barreiros T, Bertani I, Bjourson A J, Brückner M, Bruschi C V, Carignani G, Castagnoli L, Cerdan E, Clemente M L, Coblenz A, Coglievina M, Coissac E, Defoor E, Del Bino S, Delius H, Delneri D, de Wergifosse P, Dujon B, Kleine K
Unité de Biochimie Physiologique, Université Catholique de Louvain, Louvain-la-Neuve, Belgium.
Nature. 1997 May 29;387(6632 Suppl):81-4.
The complete nucleotide sequence of Saccharomyces cerevisiae chromosome VII has 572 predicted open reading frames (ORFs), of which 341 are new. No correlation was found between G+C content and gene density along the chromosome, and their variations are random. Of the ORFs, 17% show high similarity to human proteins. Almost half of the ORFs could be classified in functional categories, and there is a slight increase in the number of transcription (7.0%) and translation (5.2%) factors when compared with the complete S. cerevisiae genome. Accurate verification procedures demonstrate that there are less than two errors per 10,000 base pairs in the published sequence.
酿酒酵母第七条染色体的完整核苷酸序列中有572个预测的开放阅读框（ORF），其中341个是新的。沿该染色体未发现鸟嘌呤与胞嘧啶（G+C）含量和基因密度之间存在相关性，它们的变化是随机的。在这些开放阅读框中，17%与人类蛋白质具有高度相似性。几乎一半的开放阅读框可归类于功能类别，与完整的酿酒酵母基因组相比，转录因子（7.0%）和翻译因子（5.2%）的数量略有增加。精确的验证程序表明，已发表序列中每10,000个碱基对的错误少于两个。
