小鼠体细胞和生殖细胞中辐射诱导易位的剂量-反应关系。
Dose-response relationship for radiation-induced translocations in somatic and germ cells of mice.
作者信息
van Buul P P
出版信息
Mutat Res. 1977 Oct;45(1):61-8. doi: 10.1016/0027-5107(77)90043-4.
PMID:917035
Abstract
Dose--response curves (0--600 rad X-rays) for induced reciprocal translocations in bone-marrow cells and in spermatogonia (scored in spermatocytes) of the mouse were constructed. The obtained results suggest that factors influencing aberration yields in somatic cells, are similar to those in germ cells and strengthen the premise for qualitative extrapolation from somatic cells to germ cells.
摘要
构建了小鼠骨髓细胞和精原细胞（在精母细胞中计分）中诱导相互易位的剂量-反应曲线（0-600拉德X射线）。所得结果表明，影响体细胞中畸变产率的因素与生殖细胞中的相似，并强化了从体细胞到生殖细胞进行定性外推的前提。
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