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小鼠体细胞和生殖细胞中辐射诱导易位的剂量-反应关系。

Dose-response relationship for radiation-induced translocations in somatic and germ cells of mice.

作者信息

van Buul P P

出版信息

Mutat Res. 1977 Oct;45(1):61-8. doi: 10.1016/0027-5107(77)90043-4.

DOI:10.1016/0027-5107(77)90043-4
PMID:917035
Abstract

Dose--response curves (0--600 rad X-rays) for induced reciprocal translocations in bone-marrow cells and in spermatogonia (scored in spermatocytes) of the mouse were constructed. The obtained results suggest that factors influencing aberration yields in somatic cells, are similar to those in germ cells and strengthen the premise for qualitative extrapolation from somatic cells to germ cells.

摘要

构建了小鼠骨髓细胞和精原细胞（在精母细胞中计分）中诱导相互易位的剂量-反应曲线（0-600拉德X射线）。所得结果表明，影响体细胞中畸变产率的因素与生殖细胞中的相似，并强化了从体细胞到生殖细胞进行定性外推的前提。

相似文献

1
Dose-response relationship for radiation-induced translocations in somatic and germ cells of mice.小鼠体细胞和生殖细胞中辐射诱导易位的剂量-反应关系。
Mutat Res. 1977 Oct;45(1):61-8. doi: 10.1016/0027-5107(77)90043-4.
2
The effect of exposure rate on translocation induction in somatic and germ cells of the mouse (Mus musculus).照射率对小鼠（小家鼠）体细胞和生殖细胞中易位诱导的影响。
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[Comparative study of reciprocal translocation frequency in the spermatocytes after the irradiation of newborn and adult mice].[新生和成年小鼠受照射后精母细胞中相互易位频率的比较研究]
Genetika. 1978 Mar;14(3):548-50.
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Dose-response data for X-ray induced translocations in spermatogonia of Rhesus monkeys.恒河猴精原细胞中X射线诱导易位的剂量反应数据。
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Effects of unequally fractionated X-ray exposures on the induction of chromosomal rearrangements in mouse spermatogonia.不等分次X射线照射对小鼠精原细胞染色体重排诱导的影响。
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A comparative study of the frequencies of radiation-induced chromosome aberrations in somatic and germ cells of the Rhesus monkey (Macaca mulatta).恒河猴（猕猴）体细胞和生殖细胞中辐射诱导染色体畸变频率的比较研究。
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Induction of an adaptive response to dominant lethality and to chromosome damage of mouse germ cells by low dose radiation.低剂量辐射诱导小鼠生殖细胞对显性致死和染色体损伤的适应性反应。
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[Mutagenic effect of radiation on mice subjected to gamma irradiation during the embryonic period. I. Frequency of reciprocal translocations in the spermatocytes of mice subjected to gamma-irradiation at different stages of embryogenesis].[辐射对胚胎期接受γ射线照射的小鼠的诱变作用。I.胚胎发育不同阶段接受γ射线照射的小鼠精母细胞中相互易位的频率]
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Dose-response relationship for x-ray-induced reciprocal translocations in stem-cell spermatogonia of the rhesus monkey (Macaca mulatta).恒河猴（猕猴）干细胞精原细胞中X射线诱导的相互易位的剂量反应关系。
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Induction of a cytogenetic adaptive response in germ cells of irradiated mice with very low-dose rate of chronic gamma-irradiation and its biological influence on radiation-induced DNA or chromosomal damage and cell killing in their male offspring.用非常低剂量率的慢性γ射线照射诱导受照小鼠生殖细胞的细胞遗传学适应性反应及其对辐射诱导的DNA或染色体损伤以及其雄性后代细胞杀伤的生物学影响。
Mutagenesis. 1995 Mar;10(2):95-100. doi: 10.1093/mutage/10.2.95.

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