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照射率对小鼠(小家鼠)体细胞和生殖细胞中易位诱导的影响。

The effect of exposure rate on translocation induction in somatic and germ cells of the mouse (Mus musculus).

作者信息

van Buul P P, Roos R A

出版信息

Mutat Res. 1977 Jan;42(1):99-107. doi: 10.1016/s0027-5107(77)80012-2.

DOI:10.1016/s0027-5107(77)80012-2
PMID:846491
Abstract

The effect of exposure rate on translocation induction in spermatogonia, scored as multivalents in descending spermatocytes and bone-marrow cells of the mouse (Mus musculus) was investigated 65--100 days after X-ray and gamma-ray exposures of 400 R. In the range of exposure rates studied there was a decreased in frequency in bone-marrow cells from 17.1% at 130 R/min to 4.6% at 0.0287 R/min. In spermatogonia the frequency dropped from 6.7% at 130 R/min to 1.9% at 0.0287 R/min. The data obtained for both tissues fitted a straight line when plotted against the logarithm of the exposure rate. The ratios between aberration frequencies in bone-marrow cells and spermatogonia, with a mean value of 2.74, were independent of exposure rate.

摘要

在对小鼠(小家鼠)进行400伦琴的X射线和γ射线照射65 - 100天后,研究了照射率对精原细胞易位诱导的影响,易位通过减数分裂后期精母细胞和骨髓细胞中的多价体来计分。在所研究的照射率范围内,骨髓细胞的频率从130伦琴/分钟时的17.1%下降到0.0287伦琴/分钟时的4.6%。在精原细胞中,频率从130伦琴/分钟时的6.7%下降到0.0287伦琴/分钟时的1.9%。当针对照射率的对数进行绘制时,两个组织获得的数据均符合一条直线。骨髓细胞和精原细胞中畸变频率的比值平均值为2.74,且与照射率无关。

相似文献

1
The effect of exposure rate on translocation induction in somatic and germ cells of the mouse (Mus musculus).照射率对小鼠(小家鼠)体细胞和生殖细胞中易位诱导的影响。
Mutat Res. 1977 Jan;42(1):99-107. doi: 10.1016/s0027-5107(77)80012-2.
2
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[Chromosome modifications induced in mouse spermatogonia through exposure to high-energy neutrons].[通过暴露于高能中子在小鼠精原细胞中诱导的染色体修饰]
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Induction of a cytogenetic adaptive response in germ cells of irradiated mice with very low-dose rate of chronic gamma-irradiation and its biological influence on radiation-induced DNA or chromosomal damage and cell killing in their male offspring.用非常低剂量率的慢性γ射线照射诱导受照小鼠生殖细胞的细胞遗传学适应性反应及其对辐射诱导的DNA或染色体损伤以及其雄性后代细胞杀伤的生物学影响。
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