Innis S M, Nelson C M, Wadsworth L D, MacLaren I A, Lwanga D
Department of Paediatrics, University of British Columbia.
Can J Public Health. 1997 Mar-Apr;88(2):80-4. doi: 10.1007/BF03403865.
The iron status and feeding practices of 434 infants in Vancouver were determined at 39 +/- 1 week of age. Iron-deficiency anaemia (haemoglobin < or = 101 g/L, or < or = 110 g/L with two or three abnormal results from tests of serum ferritin, zinc erythrocyte protoporphyrin and total iron binding capacity) occurred in 7% of infants. Low iron stores (serum ferritin < 10 micrograms/l) occurred in about 24% of infants. Iron-deficiency anaemia was significantly associated (p < 0.001) with duration of breastfeeding. The prevalence of iron-deficiency anaemia among infants breastfed for 8 months was 15%. At 39 weeks (9 months) of age, about 5% and 13% of the infants were bottle-fed with cows milk or low iron infant formula, respectively, and this was also significantly associated (p < 0.02) with low iron stores. Iron-fortified infant cereals had been introduced to 95% of the infants by six months of age. This study shows iron-deficiency anaemia is a problem among a significant number of nine-month-old infants in Canada, and is not explained by failure to introduce iron-fortified infant cereals.
对温哥华434名婴儿在39±1周龄时的铁状态和喂养方式进行了测定。缺铁性贫血（血红蛋白≤101g/L，或≤110g/L且血清铁蛋白、锌原卟啉和总铁结合力检测有两项或三项异常结果）在7%的婴儿中出现。约24%的婴儿存在铁储备不足（血清铁蛋白<10μg/L）。缺铁性贫血与母乳喂养持续时间显著相关（p<0.001）。母乳喂养8个月的婴儿中缺铁性贫血患病率为15%。在39周（9个月）龄时，分别约有5%和13%的婴儿用牛奶或低铁婴儿配方奶粉瓶喂，这也与铁储备不足显著相关（p<0.02）。到6个月龄时，95%的婴儿已开始食用铁强化婴儿谷物。这项研究表明，缺铁性贫血是加拿大相当数量9个月大婴儿中的一个问题，并非未引入铁强化婴儿谷物所致。
