安大略省北部一个城镇基于人群的乙肝血清流行率及风险因素研究。
A population-based hepatitis B seroprevalence and risk factor study in a northern Ontario town.
作者信息
Glasgow K W, Schabas R, Williams D C, Wallace E, Nalezyty L A
机构信息
Brant County Health Unit, ON.
出版信息
Can J Public Health. 1997 Mar-Apr;88(2):87-90. doi: 10.1007/BF03403867.
OBJECTIVE
To determine a) population-based hepatitis B seroprevalence rates; and b) associated behavioural risk factors.
SETTING
A remote northern Ontario town with a cluster of hepatitis B cases.
INTERVENTIONS
Anonymous blood testing linked with risk-factor questionnaires.
RESULTS
635 persons aged 14 to 30 years (51% of the eligible age cohort) donated blood in return for free vaccination; four were anti-HBs positive, and none was HBsAg positive. In all, 19% of participants reported two or more sexual partners in the previous year, 6% reported at least one tattooing in the previous year, and 1% reported illicit injection drug use. Of persons with multiple sexual partners 84% did not consistently use condoms.
CONCLUSIONS
When the serological results of the original cluster (and contacts) were considered, the age cohort's HBsAg seroprevalence rate was estimated to be between 0.24% and 0.47%. While the serosurvey did not discover additional HBsAg positive cases, there was great potential for heterosexual transmission.
目的
a）确定基于人群的乙肝血清流行率；b）确定相关行为风险因素。
地点
安大略省北部一个偏远小镇，有一批乙肝病例。
干预措施
与风险因素问卷相关的匿名血液检测。
结果
635名年龄在14至30岁之间的人（占符合条件年龄组的51%）献血以换取免费疫苗接种；4人抗-HBs呈阳性，无人HBsAg呈阳性。总体而言，19%的参与者报告在前一年有两个或更多性伴侣，6%报告在前一年至少有一次纹身，1%报告有非法注射吸毒行为。有多个性伴侣的人中，84%未始终使用避孕套。
结论
考虑到最初病例群（及接触者）的血清学结果，该年龄组的HBsAg血清流行率估计在0.24%至0.47%之间。虽然血清学调查未发现更多HBsAg阳性病例，但异性传播的可能性很大。
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