Fritz C L, Kjemtrup A M, Conrad P A, Flores G R, Campbell G L, Schriefer M E, Gallo D, Vugia D J
Division of Vector-Borne Infectious Diseases, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Fort Collins, Colorado 80522-2087, USA.
J Infect Dis. 1997 Jun;175(6):1432-9. doi: 10.1086/516476.
A seroprevalence and risk factor study of emerging tickborne infectious diseases (Lyme disease, ehrlichiosis, and babesiosis) was conducted among 230 residents of a semirural community in Sonoma County, California. Over 50% of residents reported finding a tick on themselves in the preceding 12 months. Samples from 51(23%) residents were seroreactive to antigens from one or more tickborne disease agents: 1.4% to Borrelia burgdorferi, 0.4% to Ehrlichia equi, 4.6% to Ehrlichia chaffeensis, and 17.8% to the Babesia-like piroplasm WA1. Only 14 (27%) of these seroreactive residents reported one or more symptoms compatible with these diseases. Seroreactivity was significantly associated with younger age (<16 years), longer residence in the community (11-20 years), and having had a physician's diagnosis of Lyme disease. In northern California, the risk of infection with these emerging tickborne diseases, particularly in children, may be greater than previously recognized.
在加利福尼亚州索诺马县一个半乡村社区的230名居民中开展了一项关于新出现的蜱传传染病（莱姆病、埃立克体病和巴贝斯虫病）的血清流行率及危险因素的研究。超过50%的居民报告在之前12个月内发现自己身上有蜱虫。来自51名（23%）居民的样本对一种或多种蜱传疾病病原体的抗原呈血清反应阳性：对伯氏疏螺旋体呈阳性的占1.4%，对马埃立克体呈阳性的占0.4%，对查菲埃立克体呈阳性的占4.6%，对类巴贝斯焦虫WA1呈阳性的占17.8%。这些血清反应阳性的居民中只有14名（27%）报告有一项或多项与这些疾病相符的症状。血清反应阳性与年龄较小（<16岁）、在社区居住时间较长（11 - 20年）以及曾被医生诊断为莱姆病显著相关。在加利福尼亚州北部，感染这些新出现的蜱传疾病的风险，尤其是在儿童中，可能比之前认识到的更大。
