Dingeon B, Berthaud A, Besson C, Chaberty C, Onclercq R, Panquet D
Centre Hospitalier de Chambéry.
Ann Pharm Fr. 1997;55(2):55-61.
Gender verification in sport was introduced in 1967 based on the insufficient Barr test. For Albertville's Olympic Games we proposed the Medical Commission of IOC to carry out the control for the first time thanks to molecular biochemistry. PCR/SRY amplification is described giving more than 99.9% of good results. After Albertville, Barcelona and Lillehammer the method will be used in Atlanta and Nagano. Results and ethics are discussed. Easy and respectful of athletes, this reliable gender verification is indispensable for their protection. According to the good practices of CM/IOC, samples have to be discarded after the analysis is done.
1967年，基于不充分的巴氏试验引入了体育赛事中的性别验证。对于阿尔贝维尔奥运会，由于分子生物化学技术，我们首次提议国际奥委会医学委员会进行检测。文中描述了聚合酶链反应/性别决定区Y基因扩增，其准确率超过99.9%。在阿尔贝维尔奥运会之后，巴塞罗那奥运会和利勒哈默尔奥运会也采用了该方法，之后亚特兰大奥运会和长野冬奥会也将使用。文中讨论了检测结果及伦理问题。这种可靠的性别验证方法简便且尊重运动员，对保护运动员而言必不可少。根据国际奥委会医学委员会的良好做法，检测完成后样本必须丢弃。
