Serink M T, Nachemson A, Hansson G
Acta Orthop Scand. 1977;48(3):250-62. doi: 10.3109/17453677708988764.
Eighteen mature male Whiteland rabbits received repetitive impulse loads slightly larger than body weight (4 kp) through one knee joint for periods from 1 to 6 weeks. Mechanical compression of subchondral bone cores from impacted tibiae showed progressive increased deformation under a constant force. Cartilage degeneration occurred concurrently with alterations in the mechanical properties of the subchondral bone. The cartilage degeneration may be explained by: (i) the deleterious effect of repetitive mechanical compression, (ii) the decreased mechanical support of the underlying subchondral bone.
18只成年雄性怀特兰兔通过一个膝关节接受略大于体重（4千帕）的重复性脉冲负荷，持续1至6周。对受冲击胫骨的软骨下骨核心进行机械压缩，结果显示在恒定力作用下变形逐渐增加。软骨退变与软骨下骨力学性能的改变同时发生。软骨退变可能由以下原因解释：（i）重复性机械压缩的有害作用，（ii）下方软骨下骨机械支撑的减少。
