Hoshijima K, Nightingale R W, Yu J R, Richardson W J, Harper K D, Yamamoto H, Myers B S
Kochi Medical Center, Japan.
Spine (Phila Pa 1976). 1997 Jun 1;22(11):1181-8. doi: 10.1097/00007632-199706010-00002.
A paired comparison was done of the bending flexibility and compression strength of tricortical bone graft and titanium fiber mesh implants in a human cadaver model of posterior lumbar interbody fusion.
To test the hypothesis that a titanium fiber mesh implant and a tricortical bone graft provide adequate and equal mechanical strength and stability in posterior lumbar interbody fusion constructs.
Although studies of posterior lumbar interbody fusion constructs have been performed, the authors are unaware of any study in which the strength and stability of a titanium fiber mesh implant are compared with those of tricortical bone graft for posterior lumbar interbody fusion in the human cadaver lumbar spine.
Changes in neutral zone and range of motion were measured in a bending flexibility test before and after placement of posterior lumbar interbody fusion constructs. Tricortical bone graft and titanium fiber mesh implant construct stability than were compared in a paired analysis. The constructs than were loaded to failure to evaluate construct strength as a function of graft material and bone mineral density.
The posterior lumbar interbody fusion procedure produced statistically significant decreases in neutral zone when compared with the intact spine. No statistically significant differences in neutral zone, range of motion, or strength were detected between the two implants. Construct strength correlated strongly with bone mineral density.
Posterior lumbar interbody fusion procedures result in equal or improved acute stability for titanium fiber mesh implants and tricortical bone graft implants when used without additional posterior stabilization.
在人体尸体腰椎后路椎间融合模型中,对三皮质骨移植和钛纤维网植入物的弯曲柔韧性和抗压强度进行配对比较。
检验以下假设,即钛纤维网植入物和三皮质骨移植在腰椎后路椎间融合结构中提供足够且相等的机械强度和稳定性。
尽管已对腰椎后路椎间融合结构进行了研究,但作者未发现有任何研究在人体尸体腰椎中比较钛纤维网植入物与三皮质骨移植用于腰椎后路椎间融合时的强度和稳定性。
在放置腰椎后路椎间融合结构之前和之后的弯曲柔韧性测试中,测量中立区和活动范围的变化。在配对分析中比较三皮质骨移植和钛纤维网植入物结构的稳定性。然后对这些结构加载直至失效,以评估作为移植材料和骨矿物质密度函数的结构强度。
与完整脊柱相比,腰椎后路椎间融合手术使中立区有统计学上的显著降低。两种植入物之间在中立区、活动范围或强度方面未检测到统计学上的显著差异。结构强度与骨矿物质密度密切相关。
在不使用额外后路稳定的情况下,腰椎后路椎间融合手术对钛纤维网植入物和三皮质骨移植植入物产生同等或更好的急性稳定性。