Wang K a, Zhang L B, Otten M W, Zhang X L, Yasuo C, Zhang R Z, Xu T, Liu X, Liu M, Li Q L, Yu J J, Wang Z
Chinese Academy of Preventive Medicine, Ministry of Public Health, World Health Organization, Beijing, People's Republic of China.
J Infect Dis. 1997 Feb;175 Suppl 1:S105-12. doi: 10.1093/infdis/175.supplement_1.s105.
A large nationwide outbreak occurred in 1989-1990 in China, in which nearly 10,000 poliomyelitis cases were reported. After two rounds of oral poliovirus vaccine (OPV) supplemental activity in nearly every province in the 1992-1993 winter season, no wild poliovirus was detected in 1993 in 22 provinces in the middle of China that contained 86% of the population. During the first national immunization days (NIDs) conducted in December 1993 and January 1994, 83 million children 0-47 months of age were immunized. In 1994, wild poliovirus was identified in only 6 of 2397 children with stool specimens tested. After a second NID in December 1994 and January 1995, no wild poliovirus was detected in 1995 despite a very high level of virus surveillance. In summary, double-round mass supplemental OPV immunizations in children 0-3 years old in two consecutive winters eliminated wild poliovirus from 23% of the world's population (1.2 billion people).
1989 - 1990年中国发生了一次大规模的全国性疫情，报告了近10000例脊髓灰质炎病例。在1992 - 1993年冬季几乎每个省份都开展了两轮口服脊髓灰质炎疫苗（OPV）补充活动后，1993年在中国中部占人口86%的22个省份未检测到野生脊髓灰质炎病毒。在1993年12月和1994年1月开展的首个全国免疫日（NIDs）期间，8300万0 - 47月龄儿童接受了免疫接种。1994年，在检测的2397份儿童粪便标本中，仅在6份标本中发现了野生脊髓灰质炎病毒。在1994年12月和1995年1月开展第二次全国免疫日后，尽管病毒监测水平很高，但1995年未检测到野生脊髓灰质炎病毒。总之，连续两个冬季对0 - 3岁儿童进行两轮大规模口服脊髓灰质炎疫苗补充免疫，使全球23%的人口（12亿人）中消灭了野生脊髓灰质炎病毒。
