Ganz M, Joller-Jemelka H I, Grob P J
Schweiz Med Wochenschr. 1979 Sep 22;109(36):1314-22.
In 1977 and 1978 the serum concentration of alpha-1-fetoprotein (AFP) in 3200 patients was measured for diagnostic purposes. Values above 320 ng/ml were observed in 75 patients; they underwent closer study. The final diagnoses were hepatoma (50), germ cell tumors (15), other malignant tumors (6) and acute hepatitis (4). Also, chronic hepatitis and liver coma may be associated with AFP values above 320 ng/ml. Repeated measurements usually provide further diagnostic information.
1977年至1978年期间,为诊断目的对3200名患者的血清甲胎蛋白(AFP)浓度进行了测量。75名患者的AFP值高于320 ng/ml;对他们进行了更深入的研究。最终诊断结果为肝癌(50例)、生殖细胞肿瘤(15例)、其他恶性肿瘤(6例)和急性肝炎(4例)。此外,慢性肝炎和肝昏迷也可能与AFP值高于320 ng/ml有关。重复测量通常可提供更多诊断信息。