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山竹果天然氧杂蒽酮及其合成衍生物的抗真菌活性评估。

Evaluation of the antifungal activity of natural xanthones from Garcinia mangostana and their synthetic derivatives.

作者信息

Gopalakrishnan G, Banumathi B, Suresh G

机构信息

Centre for Agrochemical Research, SPIC Science Foundations, Madras, India.

出版信息

J Nat Prod. 1997 May;60(5):519-24. doi: 10.1021/np970165u.

DOI:10.1021/np970165u
PMID:9213587
Abstract

The antifungal activity of several xanthones isolated from the fruit hulls of Garcinia mangostana and some derivatives of mangostin against three phytopathogenic fungi, Fusarium oxysporum vasinfectum, Alternaria tenuis, and Dreschlera oryzae, has been evaluated. The natural xanthones showed good inhibitory activity against the three fungi. Substitution in the A and C rings has been shown to modify the bioactivities of the compounds.

摘要

对从山竹果皮中分离出的几种氧杂蒽酮及其倒捻子素的一些衍生物针对三种植物病原真菌——尖孢镰刀菌、细交链孢菌和稻德氏霉的抗真菌活性进行了评估。天然氧杂蒽酮对这三种真菌显示出良好的抑制活性。已表明在A环和C环上进行取代会改变这些化合物的生物活性。

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