Pfennigsdorf S, Lieb W E
Augenklinik der Julius-Maximilians Universität, Würzburg.
Klin Monbl Augenheilkd. 1997 Feb;210(2):113-5. doi: 10.1055/s-2008-1035027.
Xanthomatous tumors are common tumors of the eyelid. We report the rare case of a patient with a papular xanthoma of the eyelid.
The 87-year old patient suffered from multiple xanthomatous lesion in the face and the trunk. The tumors were painless and elastic. A biopsy of the largest tumor was performed.
The histologic examination revealed multiple histiocytes and giant cells of the Touton type. Immunohistochemistry showed a positive stain for CD68.
The clinical, histologic and immunohistochemical findings are typical for a papular xanthoma and help to differentiate from other xanthomatous lesions such as xanthelasma, xanthoma disseminatum, necrobiotic xanthogranuloma and fibrous histiocytoma.
黄色瘤性肿瘤是眼睑的常见肿瘤。我们报告了1例眼睑丘疹性黄色瘤患者的罕见病例。
该87岁患者面部和躯干有多处黄色瘤性病变。肿瘤无痛且有弹性。对最大的肿瘤进行了活检。
组织学检查显示有多个组织细胞和杜顿型巨细胞。免疫组织化学显示CD68染色呈阳性。
临床、组织学和免疫组织化学表现是丘疹性黄色瘤的典型表现,有助于与其他黄色瘤性病变如睑黄瘤、播散性黄色瘤、渐进性坏死性黄色肉芽肿和纤维组织细胞瘤相鉴别。