Pott F, Knudsen L, Nowak M, Nielsen H B, Hanel B, Secher N H
Copenhagen Muscle Research Centre, Denmark.
Acta Physiol Scand. 1997 Jul;160(3):251-5. doi: 10.1046/j.1365-201X.1997.00144.x.
Dynamic exercise increases the transcranial Doppler determined mean blood velocity in basal cerebral arteries corresponding to the cortical representation of the active limb(s) and independent of the concomitant rise in the mean arterial pressure. In 12 rowers we evaluated the middle cerebral artery blood velocity response to ergometer rowing when regulation of the cerebral perfusion is challenged by stroke synchronous fluctuation in arterial pressure. Rowing increased mean cerebral blood velocity (57 +/- 3 to 67 +/- 5 cm s-1; mean +/- SE) and mean arterial (86 +/- 6 to 97 +/- 6 mmHg) and central venous pressures (0 +/- 2 to 8 +/- 2 mmHg; P < 0.05). The force on the oar triggered an averaging procedure that demonstrated stroke synchronous sinusoidal oscillations in the cerebral velocity with a 12 +/- 2% amplitude upon the average exercise value. During the catch phase of the stroke, the mean velocity increased to a peak of 88 +/- 7 cm s-1 and it was in phase with the highest mean arterial pressure (125 +/- 14 mmHg), while the central venous pressure was highest after the stroke (20 +/- 3 mmHg). The results suggest that during rowing cerebral perfusion is influenced significantly by the rapid fluctuations in the perfusion pressure.
动态运动可增加经颅多普勒测定的大脑基底动脉平均血流速度，该动脉对应于活动肢体的皮层代表区，且与平均动脉压的同时升高无关。在12名赛艇运动员中，当动脉压的卒中同步波动对脑灌注调节构成挑战时，我们评估了他们在测力计划船时大脑中动脉的血流速度反应。划船增加了大脑平均血流速度（从57±3厘米/秒增至67±5厘米/秒；平均值±标准误）、平均动脉压（从86±6毫米汞柱增至97±6毫米汞柱）和中心静脉压（从0±2毫米汞柱增至8±2毫米汞柱；P<0.05）。桨上的力触发了一种平均程序，该程序显示大脑血流速度出现卒中同步正弦振荡，平均运动值时的振荡幅度为12±2%。在划桨的抓水阶段，平均血流速度增加至峰值88±7厘米/秒，且与最高平均动脉压（125±14毫米汞柱）同步，而中心静脉压在划桨后最高（20±3毫米汞柱）。结果表明，划船过程中脑灌注受灌注压快速波动的显著影响。
