Ricci C, Vaccari S, Cavalli M, Vincenzi C
Department of Dermatology, University of Bologna, Italy.
Am J Contact Dermat. 1997 Sep;8(3):165-6.
Para aminobenzoic acid (PABA) derivatives and cinnamate are chemical sunscreens that protect against UVB (290 to 320 nm). They may occasionally produce contact and photocontact sensitization.
To report a sensitization to octyl-dimethyl-PABA and photosensitization to 2-ethylhexyl-p-metossicinnamate in a 31-year-old man.
A patient with a 3-year history of a relapsing dermatitis involving the face, neck, legs, and knees is reported. The eruption had recurred every summer after sunlight exposure. Patch tests with International Contact Dermatitis Research Group (IC-DRG) standard series and the photopatch series (Hermal-Trolab, Reinbek, Germany) using Finn chambers on Scanpor (Norgesplaster A/S, Oslo, Norway) were carried out.
We found a positive reaction to Balsam of Peru, fragrance mix, Escalol 507, and Parsol MCX (Hermal-Trolab, Reinbek, Germany). Photopatch test revealed a positive reaction only for Parsol MCX.
The incidence of allergic contact dermatitis to sunscreens is considered low. Recently sunscreens patch test concentrations have been increased from 2% to 10%. These higher percentages will probably permit the identification of more cases of sunscreens allergy in the near future.
对氨基苯甲酸（PABA）衍生物和桂皮酸盐是可抵御中波紫外线（290至320纳米）的化学防晒剂。它们偶尔会引起接触性和光接触性过敏。
报告一名31岁男性对辛基二甲基对氨基苯甲酸过敏及对2-乙基己基对甲氧基肉桂酸酯光过敏的情况。
报告一名有3年复发性皮炎病史的患者，其皮疹累及面部、颈部、腿部和膝盖。皮疹每年夏季日光照射后都会复发。使用Scanpor（挪威奥斯陆Norgesplaster A/S公司）上的Finn小室，对该患者进行了国际接触性皮炎研究组（IC-DRG）标准系列和光变应原系列（德国赖因贝克Hermal-Trolab公司）的斑贴试验。
我们发现患者对秘鲁香脂、香料混合物、埃斯卡洛尔507和帕索1789（德国赖因贝克Hermal-Trolab公司）呈阳性反应。光变应原斑贴试验仅显示对帕索1789呈阳性反应。
对防晒剂发生过敏性接触性皮炎的发生率被认为较低。最近，防晒剂斑贴试验的浓度已从2%提高到10%。这些更高的百分比可能会在不久的将来使更多防晒剂过敏病例得以确诊。
