Funaki S, Shirakashi M, Abe H
Department of Ophthalmology, Niigata University School of Medicine, Japan.
Nippon Ganka Gakkai Zasshi. 1997 Jul;101(7):598-604.
We measured the area of parapapillary chorioretinal atrophy (PPA), i.e. zone alpha and zone beta in fluorescein angiography, and parapapillary avascular area (PPAVA) in indocyanine green angiography, using scanning laser ophthalmoscope in a total of 66 eyes of 39 patients. There were 26 eyes of 16 patients with normal tension glaucoma (NTG) and 40 eyes of 23 patients with primary open angle glaucoma (POAG). Although there was no significant correlation between the areas of PPAVA, PPA, zone alpha or zone beta, and mean deviation of Humphrey field analysis, there was significant correlation between all areas except for zone alpha and the spherical equivalent. The areas of PPAVA and zone beta in the NTG group were significantly larger than those in the POAG group (p = 0.04434, 0.02750, respectively). These results suggest that the pathogenesis of disease may be different in NTG and POAG.
我们使用扫描激光检眼镜，对39例患者的66只眼进行了测量，测定了视盘旁脉络膜视网膜萎缩（PPA）的面积，即荧光素血管造影中的α区和β区，以及吲哚菁绿血管造影中的视盘旁无血管区（PPAVA）。其中有16例正常眼压性青光眼（NTG）患者的26只眼，以及23例原发性开角型青光眼（POAG）患者的40只眼。尽管PPAVA、PPA、α区或β区的面积与Humphrey视野分析的平均偏差之间无显著相关性，但除α区外的所有区域与等效球镜度之间存在显著相关性。NTG组的PPAVA和β区面积显著大于POAG组（p分别为0.04434和0.02750）。这些结果表明，NTG和POAG的发病机制可能不同。
