Brown S J, Child R B, Day S H, Donnelly A E
Exercise Physiology Laboratory, School of Health Sciences, University of Wolverhampton, UK.
J Sports Sci. 1997 Apr;15(2):215-22. doi: 10.1080/026404197367498.
Repeated bouts of eccentric muscle contractions were used to examine indirect indices of exercise-induced muscle damage and adaptation in human skeletal muscle. Twenty-four subjects (18 females, 6 males) aged 20.0 +/- 1.4 years (mean +/- S.D.) performed an initial bout of either 10 (n = 7), 30 (n = 9) or 50 (n = 8) maximum voluntary eccentric contractions of the knee extensors, followed by a second bout of 50 contractions 3 weeks later using the same leg. Muscle soreness was elevated after all bouts (P < 0.05, Wilcoxon test), although the initial bout reduced the soreness associated with the second bout. Force loss and a decline in the 20:100 Hz percutaneous electrical myostimulation force ratio were observed after all exercise bouts (P < 0.01). Serum creatine kinase activity was elevated following the initial bouts of 30 and 50 repetitions (P < 0.01), but there was no increase following 10 repetitions. No increase in serum creatine kinase activity was observed in any group following the second bout of contractions (P > 0.05). We conclude that skeletal muscle adaptation can be brought about by a single bout of relatively few eccentric muscle contractions. Increasing the number of eccentric muscle repetitions did not result in an increased prophylactic effect on skeletal muscle.
通过反复进行离心性肌肉收缩来检测运动诱导的人类骨骼肌损伤和适应性的间接指标。24名年龄在20.0±1.4岁（均值±标准差）的受试者（18名女性，6名男性）对膝伸肌进行了初始的一组10次（n = 7）、30次（n = 9）或50次（n = 8）的最大自主离心收缩，然后在3周后用同一条腿进行第二组50次收缩。所有组运动后肌肉酸痛均加剧（P < 0.05，Wilcoxon检验），尽管初始组运动减轻了与第二组运动相关的酸痛。所有运动组后均观察到力量损失以及20:100 Hz经皮电肌肉刺激力量比值下降（P < 0.01）。初始30次和50次重复运动后血清肌酸激酶活性升高（P < 0.01），但10次重复运动后未升高。第二组收缩后，任何组的血清肌酸激酶活性均未升高（P > 0.05）。我们得出结论，单次相对较少次数的离心性肌肉收缩即可引起骨骼肌适应性变化。增加离心性肌肉重复次数并未对骨骼肌产生更大的预防作用。
