Laurila A L, Von Hertzen L, Saikku P
National Public Health Institute, Oulu, Finland.
Scand J Infect Dis Suppl. 1997;104:34-6.
Chlamydia pneumoniae infection has been implicated in several chronic lung diseases by serology and direct antigen detection. Acute lower respiratory tract infection caused by C. pneumoniae seems often to precede attacks of asthma in both children and adults. Chlamydia pneumoniae is also involved in some exacerbations of chronic bronchitis and chronic obstructive lung disease but, more importantly, seems to be strongly associated with the latter irrespective of exacerbation status. Moreover, persistently elevated C. pneumoniae antibody titres have been observed in sarcoidosis and lung cancer.
通过血清学和直接抗原检测发现，肺炎衣原体感染与多种慢性肺部疾病有关。肺炎衣原体引起的急性下呼吸道感染似乎常常先于儿童和成人哮喘发作。肺炎衣原体还与慢性支气管炎和慢性阻塞性肺疾病的一些加重情况有关，但更重要的是，无论病情是否加重，它似乎都与后者密切相关。此外，在结节病和肺癌患者中也观察到肺炎衣原体抗体滴度持续升高。
