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自由生活老年人的营养状况变化及发病模式:一项为期10年的纵向研究。

Changes in nutritional status and patterns of morbidity among free-living elderly persons: a 10-year longitudinal study.

作者信息

Vellas B J, Hunt W C, Romero L J, Koehler K M, Baumgartner R N, Garry P J

机构信息

Department of Internal Medicine and Gerontology, CHU Purpan, Toulouse, France.

出版信息

Nutrition. 1997 Jun;13(6):515-9. doi: 10.1016/s0899-9007(97)00029-4.

Abstract

Nutritional intake appears to be an important factor contributing to aging. In the present study we describe changes in physical health related to nutritional intake among elderly persons in a 10-y longitudinal study. Among 304 healthy elderly participants (median age 72 y on entry into the study in 1980), 97 (34.2%) are still in good health 10 y later in 1990, 74 (26.5%) have become frail or sick, 54 (19.1%) have died, and 57 (20.1%) have dropped out of the study. Women with lower or higher energy intakes (in 1980 and 1981) than the current Recommended Daily Allowance (RDA; between 25 and 30 kcal/kg) were more likely to become frail or sick or to die in 1990 than those with energy intake in the midrange (below RDA, odds ratio (OR) = 3.3, confidence interval (CI) = 1.2-8.6; above RDA, OR = 3.4, CI: 1.1-10.7). Moreover, women with protein intakes greater than the midrange of 0.8-1.2 g/kg of body weight (1.20-1.76 g/kg in 1980 and 1981) tended to have fewer health problems over the next 10 y than those with protein intakes < 0.8 g/kg, suggesting that the mean protein requirement in elderly adults is greater than that established by the 1985 joint World Health Organization/ FAO/UNU Expert Committee. Moreover, a decrease in energy intake was greater in elderly persons who died or dropped out of the study because of illness.

摘要

营养摄入似乎是导致衰老的一个重要因素。在本研究中,我们在一项为期10年的纵向研究中描述了老年人营养摄入与身体健康变化之间的关系。在304名健康的老年参与者中(1980年进入研究时的中位年龄为72岁),97人(34.2%)在1990年10年后仍健康状况良好,74人(26.5%)变得虚弱或生病,54人(19.1%)死亡,57人(20.1%)退出了研究。1980年和1981年能量摄入量低于或高于当前推荐每日摄入量(RDA;25至30千卡/千克之间)的女性,在1990年比能量摄入量处于中等范围的女性更有可能变得虚弱或生病或死亡(低于RDA,比值比(OR)=3.3,置信区间(CI)=1.2 - 8.6;高于RDA,OR = 3.4,CI:1.1 - 也有少数情况是,在某些特定的文化或社会背景下,一些看似不合理的行为或观念可能有着深层次的功能或意义。例如,某些宗教仪式或传统习俗,从表面上看可能只是一种形式,但实际上它们在凝聚群体、传承文化、提供心理慰藉等方面发挥着重要作用。

此外,蛋白质摄入量高于体重0.8 - 1.2克/千克中等范围(1980年和1981年为1.20 - 1.76克/千克)的女性在接下来的10年中往往比蛋白质摄入量<0.8克/千克的女性健康问题更少,这表明老年人的平均蛋白质需求量大于1985年世界卫生组织/粮农组织/联合国大学联合专家委员会确定的需求量。此外,因疾病死亡或退出研究的老年人能量摄入量下降幅度更大。 10.7)。

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