与肯尼亚儿童持续性腹泻相关的多重耐药性肠聚集性大肠杆菌
Multidrug-resistant enteroaggregative Escherichia coli associated with persistent diarrhea in Kenyan children.
作者信息
Sang W K, Oundo J O, Mwituria J K, Waiyaki P G, Yoh M, Iida T, Honda T
机构信息
Kenya Medical Research Institute, Nairobi, Kenya.
出版信息
Emerg Infect Dis. 1997 Jul-Sep;3(3):373-4. doi: 10.3201/eid0303.970317.
Abstract
To study the association of multidrug-resistant enteroaggregative Escherichia coli with persistent diarrhea in Kenyan children, stool specimens were obtained from 862 outpatients under 5 years of age from July 1991 to June 1993. E. coli O44 was identified as the sole bacterial pathogen in four patients experiencing at least 14 days of fever, vomiting, and diarrhea. Disk diffusion testing showed E. coli O44 resistance to tetracycline, ampicillin, erythromycin, trimethoprim-sulphamethoxazole, and amoxicillin/clavulanate and sensitivity to chloramphenicol, nalidixic acid, azithromycin, and cefuroxime. Further studies are needed to clarify the epidemiology, clinical spectrum, and pathogenesis of enteroaggregative E. coli infection.
摘要
为研究多重耐药性肠聚集性大肠杆菌与肯尼亚儿童持续性腹泻之间的关联，于1991年7月至1993年6月从862名5岁以下门诊患儿中采集了粪便标本。在4名经历至少14天发热、呕吐和腹泻的患儿中，大肠杆菌O44被鉴定为唯一的细菌病原体。纸片扩散试验显示大肠杆菌O44对四环素、氨苄西林、红霉素、甲氧苄啶 - 磺胺甲恶唑和阿莫西林/克拉维酸耐药，对氯霉素、萘啶酸、阿奇霉素和头孢呋辛敏感。需要进一步研究以阐明肠聚集性大肠杆菌感染的流行病学、临床谱和发病机制。
相似文献
1
Multidrug-resistant enteroaggregative Escherichia coli associated with persistent diarrhea in Kenyan children.与肯尼亚儿童持续性腹泻相关的多重耐药性肠聚集性大肠杆菌
Emerg Infect Dis. 1997 Jul-Sep;3(3):373-4. doi: 10.3201/eid0303.970317.
2
Multidrug resistant enteroaggregative Escherichia coli diarrhoea in rural southern Indian population.印度南部农村人群中的多重耐药性聚集性大肠杆菌腹泻
Scand J Infect Dis. 2009;41(2):105-8. doi: 10.1080/00365540802641856.
3
Drug-resistant diarrheogenic Escherichia coli, Mexico.耐药性致泻性大肠杆菌，墨西哥
Emerg Infect Dis. 2005 Aug;11(8):1306-8. doi: 10.3201/eid1108.050192.
4
Characterization of enteroaggregative Escherichia coli (EAEC) clinical isolates and their antibiotic resistance pattern.肠聚集性大肠杆菌（EAEC）临床分离株的特性及其抗生素耐药模式。
Int J Infect Dis. 2011 Feb;15(2):e136-9. doi: 10.1016/j.ijid.2010.10.002. Epub 2010 Dec 3.
5
Detection of virulence-related genes by multiplex PCR in multidrug-resistant diarrhoeagenic Escherichia coli isolates from Kenya and Japan.采用多重聚合酶链反应检测肯尼亚和日本耐多药致泻性大肠杆菌分离株中的毒力相关基因。
Epidemiol Infect. 2005 Aug;133(4):627-33. doi: 10.1017/s0950268805003870.
6
Prevalence of diarrhoeagenic Escherichia coli in Kenyan children.肯尼亚儿童中致泻性大肠杆菌的流行情况。
J Diarrhoeal Dis Res. 1996 Sep;14(3):216-7.
7
8
9
Evolution of antimicrobial resistance in enteroaggregative Escherichia coli and enterotoxigenic Escherichia coli causing traveller's diarrhoea.引起旅行者腹泻的肠聚集性大肠杆菌和产肠毒素大肠杆菌中抗菌药物耐药性的演变
J Antimicrob Chemother. 2009 Aug;64(2):343-7. doi: 10.1093/jac/dkp178. Epub 2009 May 27.
10
Escherichia coli pathotypes associated with diarrhea in Romanian children younger than 5 years of age.与罗马尼亚5岁以下儿童腹泻相关的大肠杆菌致病型
Jpn J Infect Dis. 2009 Jul;62(4):289-93.
引用本文的文献
1
Antibiotic sensitivity profile of bacterial isolates from stool samples among children below five years in Murang'a County, Kenya.肯尼亚马朗县五岁以下儿童粪便样本中分离菌的抗生素敏感性分析。
Pan Afr Med J. 2023 Jun 20;45:87. doi: 10.11604/pamj.2023.45.87.17909. eCollection 2023.
2
Molecular Epidemiology of Enteroaggregative (EAEC) Isolates of Hospitalized Children from Bolivia Reveal High Heterogeneity and Multidrug-Resistance.玻利维亚住院儿童肠聚集性（EAEC）分离株的分子流行病学研究显示高度异质性和多重耐药性。
Int J Mol Sci. 2020 Dec 15;21(24):9543. doi: 10.3390/ijms21249543.
3
Characterization of Diarrheagenic Enteroaggregative in Danish Adults-Antibiotic Treatment Does Not Reduce Duration of Diarrhea.丹麦成年人肠聚集性腹泻的特征-抗生素治疗并不能缩短腹泻病程。
Front Cell Infect Microbiol. 2018 Sep 27;8:306. doi: 10.3389/fcimb.2018.00306. eCollection 2018.
4
Genetic Virulence Profile of Enteroaggregative Strains Isolated from Danish Children with Either Acute or Persistent Diarrhea.从丹麦急性或持续性腹泻儿童中分离出的聚集性大肠杆菌菌株的遗传毒力谱
Front Cell Infect Microbiol. 2017 May 30;7:230. doi: 10.3389/fcimb.2017.00230. eCollection 2017.
5
Prevalence, seasonal variation, and antibiotic resistance pattern of enteric bacterial pathogens among hospitalized diarrheic children in suburban regions of central Kenya.肯尼亚中部郊区住院腹泻儿童肠道细菌病原体的患病率、季节变化及抗生素耐药模式
Trop Med Health. 2016 Nov 29;44:39. doi: 10.1186/s41182-016-0038-1. eCollection 2016.
6
Increased carriage of macrolide-resistant fecal E. coli following mass distribution of azithromycin for trachoma control.在大规模分发阿奇霉素以控制沙眼后，耐大环内酯类粪便大肠杆菌的携带率增加。
Int J Epidemiol. 2014 Aug;43(4):1105-13. doi: 10.1093/ije/dyu062. Epub 2014 Mar 21.
7
Aetiology of diarrhoea and virulence properties of diarrhoeagenic Escherichia coli among patients and healthy subjects in southeast Nigeria.尼日利亚东南部患者及健康受试者中腹泻性大肠杆菌的腹泻病因及毒力特性
J Health Popul Nutr. 2010 Jun;28(3):245-52. doi: 10.3329/jhpn.v28i3.5551.
8
Complete genome sequence and comparative metabolic profiling of the prototypical enteroaggregative Escherichia coli strain 042.原型肠聚集性大肠杆菌 042 株的全基因组序列和比较代谢组学分析。
PLoS One. 2010 Jan 20;5(1):e8801. doi: 10.1371/journal.pone.0008801.
9
Antibiotic resistance in diarrheagenic Escherichia coli and Shigella strains isolated from children in Hanoi, Vietnam.从越南河内儿童中分离出的致泻性大肠杆菌和志贺氏菌菌株的抗生素耐药性
Antimicrob Agents Chemother. 2005 Feb;49(2):816-9. doi: 10.1128/AAC.49.2.816-819.2005.
10
Virulence characteristics and molecular epidemiology of enteroaggregative Escherichia coli isolates from hospitalized diarrheal patients in Kolkata, India.印度加尔各答住院腹泻患者分离出的肠聚集性大肠杆菌的毒力特征及分子流行病学
J Clin Microbiol. 2004 Sep;42(9):4111-20. doi: 10.1128/JCM.42.9.4111-4120.2004.
本文引用的文献
1
Distinctive patterns of adherence of enteropathogenic Escherichia coli to HeLa cells.肠致病性大肠杆菌对HeLa细胞的独特黏附模式。
Infect Immun. 1984 Aug;45(2):534-6. doi: 10.1128/iai.45.2.534-536.1984.
2
Antibiotic susceptibility testing by a standardized single disk method.采用标准化单纸片法进行抗生素敏感性试验。
Am J Clin Pathol. 1966 Apr;45(4):493-6.
3
Major factors in diarrhoea related mortality among rural children.农村儿童腹泻相关死亡的主要因素。
Indian J Med Res. 1986 Jan;83:9-12.
4
Escherichia coli that cause diarrhea: enterotoxigenic, enteropathogenic, enteroinvasive, enterohemorrhagic, and enteroadherent.引起腹泻的大肠杆菌：产肠毒素型、致病性、侵袭性、出血性和黏附性。
J Infect Dis. 1987 Mar;155(3):377-89. doi: 10.1093/infdis/155.3.377.
5
Patterns of adherence of diarrheagenic Escherichia coli to HEp-2 cells.致泻性大肠杆菌对HEp-2细胞的黏附模式。
Pediatr Infect Dis J. 1987 Sep;6(9):829-31. doi: 10.1097/00006454-198709000-00008.
6
Enteroaggregative Escherichia coli associated with persistent diarrhea in a cohort of rural children in India.印度一组农村儿童中与持续性腹泻相关的聚集性大肠杆菌
J Infect Dis. 1989 Jun;159(6):1061-4. doi: 10.1093/infdis/159.6.1061.
7
Rapid and specific detection of verotoxin genes in Escherichia coli by the polymerase chain reaction.利用聚合酶链反应快速、特异性检测大肠杆菌中的志贺毒素基因。
J Clin Microbiol. 1990 Mar;28(3):540-5. doi: 10.1128/jcm.28.3.540-545.1990.
8
Detection of a heat-labile enterotoxin gene in enterotoxigenic Escherichia coli by densitometric evaluation using highly specific enzyme-linked oligonucleotide probes.使用高特异性酶联寡核苷酸探针通过光密度测定评估法检测产肠毒素大肠杆菌中的热不稳定肠毒素基因。
Eur J Clin Microbiol Infect Dis. 1991 Dec;10(12):1048-55. doi: 10.1007/BF01984927.
9
Drug resistance and adherence to human intestines of enteroaggregative Escherichia coli.肠聚集性大肠杆菌对人类肠道的耐药性及黏附性
J Infect Dis. 1992 Apr;165(4):744-9. doi: 10.1093/infdis/165.4.744.
10
Vero response to a cytotoxin of Escherichia coli.Vero细胞对大肠杆菌细胞毒素的反应。
Infect Immun. 1977 Dec;18(3):775-9. doi: 10.1128/iai.18.3.775-779.1977.
Zotero 插件