Baldock F C, Flucke W J, Hopkins T J
Res Vet Sci. 1977 Sep;23(2):237-8.
Praziquantel (2 - cyclohexylcarbonyl - 1,3,4,6,7,11b - hexahydro - 2H - pyrazino (2,1 - a) isoquinolin - 4 - one) was tested against artificially established infections of Taenia hydatigena in 39 dogs. The formulation used was a 660 mg tablet containing 50 mg of active ingredient (ai). A single oral dose at 1 mg/kg ai completely removed 14-day-old infections in all dogs. 2.5 mg/kg ai praziquantel was completely effective against 7, 14 and 28-day-old worms. 5 mg/kg ai completely removed two-day-old infestations. No side effects were seen in any treated dog.
吡喹酮（2-环己基羰基-1,3,4,6,7,11b-六氢-2H-吡嗪并[2,1-a]异喹啉-4-酮）针对39只犬人工感染的泡状带绦虫进行了试验。使用的制剂为每片660毫克，含50毫克活性成分（ai）。1毫克/千克活性成分的单次口服剂量可使所有犬的14日龄感染完全消除。2.5毫克/千克活性成分的吡喹酮对7日龄、14日龄和28日龄的虫体完全有效。5毫克/千克活性成分可完全消除2日龄的感染。在任何接受治疗的犬中均未观察到副作用。
