一例乳腺外Paget病三联征病例。

A case of triple extramammary Paget's disease.

作者信息

Koseki S, Mitsuhashi Y, Yoshikawa K, Kondo S

机构信息

Department of Dermatology, Yamagata University School of Medicine, Japan.

出版信息

J Dermatol. 1997 Aug;24(8):535-8. doi: 10.1111/j.1346-8138.1997.tb02835.x.

DOI:10.1111/j.1346-8138.1997.tb02835.x

PMID:9301148

Abstract

We report a 74-year-old Japanese man with triple extramammary Paget's disease; the genital and both of the axillar regions were simultaneously involved. Literature review revealed that 27 cases of triple extramammary Paget's disease have been reported in Japan, but there are no reports of triple extramammary Paget's disease from countries other than Japan, although 2 cases of double extramammary Paget's disease are reported. In all 28 cases, including our case, the genital lesion preceded the axillary lesions. All cases except one were male and only the exceptional female case was reported to have an the invasive tumor in the dermis. We speculate that extramammary Paget's disease may appear multi-centrically.

摘要

我们报告了一名74岁的日本男性患有三发性乳腺外佩吉特病；生殖器和双侧腋窝区域同时受累。文献回顾显示，日本已报道27例三发性乳腺外佩吉特病，但除日本外其他国家尚无三发性乳腺外佩吉特病的报道，不过有2例双发性乳腺外佩吉特病的报道。在包括我们病例在内的所有28例病例中，生殖器病变先于腋窝病变出现。除1例病例外，所有病例均为男性，仅这例例外的女性病例被报道在真皮层有浸润性肿瘤。我们推测乳腺外佩吉特病可能多中心出现。