Rappley M D
Department of Pediatrics and Human Development, College of Human Medicine, Michigan State University, East Lansing, USA.
Drug Saf. 1997 Sep;17(3):143-8. doi: 10.2165/00002018-199717030-00001.
Methylphenidate is the most widely use psychotropic medication in children in the US. It is both well tolerated and efficacious in the treatment of attention deficit hyperactivity disorder, and is associated with few serious adverse effects. However, the abuse of methylphenidate for the purpose of experiencing a 'high' is hazardous. The use of methylphenidate in combination with other medications increases the risk of adverse effects and drug interactions. Good communication between the physician, patient and family, together with monitoring, increases the likelihood that methylphenidate therapy will be effective and have no adverse consequences.
哌甲酯是美国儿童中使用最广泛的精神药物。它在治疗注意力缺陷多动障碍方面耐受性良好且疗效显著，严重不良反应较少。然而，滥用哌甲酯以寻求“快感”是有害的。将哌甲酯与其他药物联合使用会增加不良反应和药物相互作用的风险。医生、患者和家属之间的良好沟通以及监测，会增加哌甲酯治疗有效的可能性且不会产生不良后果。
