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大学生滥用兴奋剂药物:综合回顾和荟萃分析。

Misuse of stimulant medication among college students: a comprehensive review and meta-analysis.

机构信息

Department of Psychology, Barnwell College, University of South Carolina, Columbia, SC, 29208, USA.

出版信息

Clin Child Fam Psychol Rev. 2015 Mar;18(1):50-76. doi: 10.1007/s10567-014-0177-z.

DOI:10.1007/s10567-014-0177-z
PMID:25575768
Abstract

The misuse of stimulant medication among college students is a prevalent and growing problem. The purpose of this review and meta-analysis is to summarize the current research on rates and demographic and psychosocial correlates of stimulant medication misuse among college students, to provide methodological guidance and other ideas for future research, and to provide some preliminary suggestions for preventing and reducing misuse on college campuses. Random-effects meta-analysis found that the rate of stimulant medication misuse among college students was estimated at 17 % (95 % CI [0.13, 0.23], p < .001) and identified several psychological variables that differentiated misusers and nonusers, including symptoms of attention-deficit/hyperactivity disorder, problems associated with alcohol use, and marijuana use. A qualitative review of the literature also revealed that Greek organization membership, academic performance, and other substance use were associated with misuse. Students are misusing primarily for academic reasons, and the most common source for obtaining stimulant medication is peers with prescriptions. Interpretation of findings is complicated by the lack of a standard misuse definition as well as validated tools for measuring stimulant misuse. The relation between stimulant medication misuse and extra curricular participation, academic outcomes, depression, and eating disorders requires further investigation, as do the reasons why students divert or misuse and whether policies on college campuses contribute to the high rates of misuse among students. Future research should also work to develop and implement effective prevention strategies for reducing the diversion and misuse of stimulant medication on college campuses.

摘要

大学生兴奋剂药物滥用是一个普遍且日益严重的问题。本综述和荟萃分析的目的是总结目前关于大学生兴奋剂药物滥用的发生率以及人口统计学和心理社会相关性的研究,为未来的研究提供方法学指导和其他思路,并为大学校园预防和减少药物滥用提供一些初步建议。随机效应荟萃分析发现,大学生兴奋剂药物滥用的发生率估计为 17%(95%CI[0.13,0.23],p<0.001),并确定了一些区分滥用者和非滥用者的心理变量,包括注意缺陷/多动障碍症状、与酒精使用相关的问题和大麻使用。文献的定性回顾还表明,希腊组织成员身份、学业成绩和其他物质使用与药物滥用有关。学生主要出于学术原因滥用兴奋剂,获得兴奋剂药物的最常见来源是有处方的同龄人。由于缺乏标准的滥用定义以及用于测量兴奋剂滥用的有效工具,对发现的解释变得复杂。兴奋剂药物滥用与课外活动参与、学业成绩、抑郁和饮食失调之间的关系需要进一步研究,还需要研究学生转移或滥用的原因,以及大学校园的政策是否导致学生滥用率高。未来的研究还应致力于制定和实施有效的预防策略,以减少大学校园兴奋剂药物的转移和滥用。

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Stimulant treatment of ADHD and cigarette smoking: a meta-analysis.兴奋剂治疗 ADHD 与吸烟行为:一项荟萃分析。
Pediatrics. 2014 Jun;133(6):1070-80. doi: 10.1542/peds.2014-0179. Epub 2014 May 12.
2
Misuse of prescription stimulants among college students: a review of the literature and implications for morphological and cognitive effects on brain functioning.大学生中处方兴奋剂的滥用:文献综述及其对大脑功能的形态学和认知影响
Exp Clin Psychopharmacol. 2013 Oct;21(5):385-407. doi: 10.1037/a0034013.
3
Prevention and treatment of college student drug use: A review of the literature.
Stimulant medications affect arousal and reward, not attention.刺激性药物影响唤醒和奖赏,而非注意力。
bioRxiv. 2025 May 22:2025.05.19.654915. doi: 10.1101/2025.05.19.654915.
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Acute Administration of 10 mg Methylphenidate on Cognitive Performance and Visual Scanning in Healthy Adults: Randomised, Double-Blind, Placebo-Controlled Study.10毫克哌甲酯对健康成年人认知表现和视觉扫描的急性给药:随机、双盲、安慰剂对照研究。
Hum Psychopharmacol. 2025 Mar;40(2):e70002. doi: 10.1002/hup.70002.
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The Issue of "Smart Drugs" on the Example of Modafinil: Toxicological Analysis of Evidences and Biological Samples.以莫达非尼为例谈“聪明药”问题:证据及生物样本的毒理学分析
J Xenobiot. 2025 Jan 17;15(1):15. doi: 10.3390/jox15010015.
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Trends in Prescription of Stimulants and Narcoleptic Drugs in Switzerland: Longitudinal Health Insurance Claims Analysis for the Years 2014-2021.瑞士兴奋剂和发作性睡病药物的处方趋势:2014 - 2021年纵向健康保险理赔分析
JMIR Public Health Surveill. 2025 Jan 7;11:e53957. doi: 10.2196/53957.
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Vilazodone, a Novel SSRI Antidepressant with 5-HT1A Partial Agonist Properties: Diminished Potentiation of Chronic Oral Methylphenidate-Induced Dynorphin Expression in the Striatum in Adolescent Male Rats.维拉唑酮,一种具有5-羟色胺1A受体部分激动剂特性的新型选择性5-羟色胺再摄取抑制剂:青春期雄性大鼠纹状体中慢性口服哌醋甲酯诱导的强啡肽表达增强作用减弱。
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