乙肝表面抗原抗体的持续性
Persistence of antibody to hepatitis B surface antigen.
作者信息
Irwin G R, Allen A M, Segal H E, Willhight M, Cannon H, Top F H
出版信息
J Clin Microbiol. 1976 May;3(5):465-8. doi: 10.1128/jcm.3.5.465-468.1976.
Sera from military personnel found to have antibodies to hepatitis B surface antigen (anti-HBS) in an epidemiological study of a hepatitis B outbreak were tested for persistence of that antibody 1 year later. Initially, 64% of the anti-HBS-positive sera reacted in passive hemagglutination tests with erythrocytes coated with hepatitis B surface antigen of both ayw and adw subtypes; the remaining sera reacted only with adw-coated erythrocytes (19%) or ayw-coated erythrocytes (17%). After 1 year, anti-HBS was detectable by passive hemagglutination tests in 87% of individuals with initial antibody to both subtypes but in only 41% and 16% (P less than 0.001) of those initially reacting only to adw- or ayw-coated erythrocytes, respectively. Seropositivity for anti-HBS correlated best with history of contact with jaundiced people (20.3%) and duty in Asia.
在一次乙型肝炎暴发的流行病学研究中，对被发现具有乙型肝炎表面抗原抗体（抗-HBS）的军人血清进行检测，以观察1年后该抗体的持续情况。最初，64%的抗-HBS阳性血清在被动血凝试验中与包被了ayw和adw亚型乙型肝炎表面抗原的红细胞发生反应；其余血清仅与包被adw的红细胞（19%）或包被ayw的红细胞（17%）发生反应。1年后，通过被动血凝试验在最初对两种亚型均有抗体的个体中87%可检测到抗-HBS，但在最初仅对包被adw或ayw红细胞发生反应的个体中分别只有41%和16%可检测到（P小于0.001）。抗-HBS血清阳性与接触黄疸患者的病史（20.3%）和在亚洲服役关联性最强。
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