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单绒毛膜双胎妊娠的隐匿性死亡率

The hidden mortality of monochorionic twin pregnancies.

作者信息

Sebire N J, Snijders R J, Hughes K, Sepulveda W, Nicolaides K H

机构信息

Harris Birthright Research Centre for Fetal Medicine, King's College Hospital Medical School, Denmark Hill, London, UK.

出版信息

Br J Obstet Gynaecol. 1997 Oct;104(10):1203-7. doi: 10.1111/j.1471-0528.1997.tb10948.x.

DOI:10.1111/j.1471-0528.1997.tb10948.x
PMID:9333002
Abstract

In an ultrasound screening study at 10 to 14 weeks of gestation for measurement of fetal nuchal translucency thickness there were 102 monochorionic and 365 dichorionic twin pregnancies. In the monochorionic compared with the dichorionic pregnancies there was a higher rate of fetal loss before 24 weeks of gestation (12.2% versus 1.8%), perinatal mortality (2.8% versus 1.6%), prevalence of delivery before 32 weeks (9.2% versus 5.5%), and prevalence of birthweight below the 5th centile in both twins (7.5% versus 1.7%). However, the proportion of pregnancies with a birthweight discordancy of more than 25% was similar in the two groups (11.3% versus 12.1%).

摘要

在一项针对孕10至14周胎儿颈部透明带厚度测量的超声筛查研究中,有102例单绒毛膜双胎妊娠和365例双绒毛膜双胎妊娠。与双绒毛膜妊娠相比,单绒毛膜妊娠在妊娠24周前的胎儿丢失率更高(12.2%对1.8%)、围产儿死亡率更高(2.8%对1.6%)、32周前分娩的发生率更高(9.2%对5.5%)以及两个胎儿出生体重均低于第5百分位数的发生率更高(7.5%对1.7%)。然而,两组中出生体重差异超过25%的妊娠比例相似(11.3%对12.1%)。

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