Fenton W S, Blyler C R, Wyatt R J, McGlashan T H
Chestnut Lodge Research Institute, Rockville, MD 20850, USA.
Br J Psychiatry. 1997 Sep;171:265-8. doi: 10.1192/bjp.171.3.265.
Although movement disorders have been noted among patients never exposed to neuroleptic medications, the specificity of spontaneous dyskinesia to schizophrenia has rarely been examined.
By abstracting detailed case records, we compared the prevalence of dyskinetic movements between 94 neuroleptic-naïve schizophrenic patients and 179 patients with other psychiatric disorders.
Dyskinetic movements were more common among patients with schizophrenia than among those with all other diagnoses, and were most often noted in the body areas typically associated with tardive dyskinesia.
Spontaneous dyskinesia appears to be relatively specific to schizophrenia and may be intrinsic to the pathophysiology of the disorder.
尽管在从未接触过抗精神病药物的患者中已发现运动障碍，但很少有人研究自发性运动障碍对精神分裂症的特异性。
通过提取详细的病例记录，我们比较了94例未使用过抗精神病药物的精神分裂症患者与179例其他精神障碍患者的运动障碍患病率。
与所有其他诊断的患者相比，精神分裂症患者的运动障碍更为常见，且最常出现在通常与迟发性运动障碍相关的身体部位。
自发性运动障碍似乎相对特异性地见于精神分裂症，可能是该疾病病理生理学所固有的。
